WBSCR1 antibody, WBSCR1 Antibody, Rabbit Polyclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

WBSCR1 Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-003-43652

Buy WBSCR1 antibody -

Size:

Trial Size Available. Please expect delivery of trial size products to be 4 weeks.

Related Product Names:

- WBSCR1 antibody; WBSCR1; EIF4H, KIAA0038, WSCR1; WBSCR1
- eIF-4H; Williams-Beuren syndrome chromosomal region 1 protein; Eukaryotic translation initiation factor 4H isoform 1; Eukaryotic translation initiation factor 4H

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: WBSCR1	Gene Name Synonym: EIF4H, KIAA0038, WSCR1
Gi #: 11559923	NCBI Acc #: NP_071496.1	Swiss Prot Acc #: Q15056
Length (aa): 248	Mol. Weight (Da): 27385	Chrom Location: N/A

Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human WBSCR1.

ELISA Titre: 1:312500

Category: RNA Binding Proteins

Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.

Source/Host: Rabbit

Purity/Purification: Rabbit IgG purified by protein A chromatography.

Clonality: Polyclonal

Crossreactivity: Human, Dog

Format: Suggested dilution at 2.5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.

Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 microl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.

Stability: Note: Avoid repeat freeze-thaw cycles.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for WBSCR1 ANTIBODY:

IHC-P. WB: Tested

TESTING: (secondary reagents and protocols [IHC Protocol])

IHC: ( anti-WBSCR1 )

WBSCR1 antibody IHC image
WBSCR1

WB: ( anti-WBSCR1 )

WBSCR1 antibody WB image
WBSCR1

WBSCR1 ANTIBODY TARGET DESCRIPTION:

Synonym Names for WBSCR1 antibody: WBSCR1; EIF4H, KIAA0038, WSCR1; eIF-4H; Williams-Beuren syndrome chromosomal region 1 protein; Eukaryotic translation initiation factor 4H isoform 1; Eukaryotic translation initiation factor 4H

WBSCR1 is one of the translation initiation factors. which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization.This gene encodes one of the translation initiation factors. which functions to stimulate the initiation

Function: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.

Subunit: Interacts with HHV-1 Vhs.

Subcellular Location: Cytoplasm, perinuclear region (By similarity).

Tissue Specificity: The short isoform is the predominant isoform and is expressed alone in liver and skeletal muscle. Both isoforms are expressed in fibroblast, spleen, testis and bone marrow. Levels are high in lung and pancreas and low in heart, frontal cortex and kidney.

Disease: Haploinsufficiency of EIF4H may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS) [MIM:194050]. WBS is a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.

Similarity: Contains 1 RRM (RNA recognition motif) domain.

Summary: This protein is one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This protein is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.

WBSCR1 reacts with human, dog.

OMIM: 194050; phenotype. [NCBI / EBI]
603431; gene. [NCBI / EBI]

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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for WBSCR1 ANTIBODY:

Background references for antibody target are not specific to GenWay products

Doepker.R.C.. (2004) J. Virol. 78 (9). 4684-4699.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: WBSCR1 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of WBSCR1 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about WBSCR1 antibody, all related information, articles, resources about WBSCR1 antibody are being stored on our online database. Let us know if you have questions regarding this product.

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