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| ALPP (alkaline phosphatase. placental (Regan isozyme)) Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-003-43718 |
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| Related Product Names:
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ALPP antibody; ALPP; PLAP; ALPP (alkaline phosphatase. placental (Regan isozyme))
- EC 3.1.3.1; PLAP-1; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase preproprotein; Alkaline phosphatase, placental type |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: ALPP |
Gene Name Synonym: PLAP |
Gi #:
94721246 |
NCBI Acc #:
NP_001623.3 |
Swiss Prot Acc #:
P05187 |
Length (aa): 535 |
Mol. Weight (Da): 57954 |
Chrom Location: N/A |
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 Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human ALPP.
ELISA Titre: 1:312500
Category: Signal Protein
Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.
Source/Host: Rabbit
Purity/Purification: Rabbit IgG purified by protein A chromatography.
Clonality: Polyclonal
Crossreactivity: Human
Format: Suggested dilution at 1.25 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.
Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.
Stability: Note: Avoid repeat freeze-thaw cycles.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for ALPP ANTIBODY: |
| IHC-P. WB: Tested |
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| ALPP ANTIBODY TARGET DESCRIPTION: |
Synonym Names for ALPP antibody: ALPP; PLAP; EC 3.1.3.1; PLAP-1; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase preproprotein; Alkaline phosphatase, placental type
There are at least four distinct but related alkaline phosphatases: intestinal. placental. placental-like. and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on c
Catalytic Activity: A phosphate monoester + H2O = an alcohol + phosphate.
Cofactor: Binds 1 magnesium ion (By similarity).
Cofactor: Binds 2 zinc ions (By similarity).
Subunit: Homodimer.
Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor.
Polymorphism: Placental ALP is highly polymorphic, there are at least three common alleles.
Miscellaneous: In most mammals there are four different isozymes: placental, placental-like, intestinal and tissue non-specific (liver/bone/kidney).
Similarity: Belongs to the alkaline phosphatase family.
Summary: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
ALPP (alkaline phosphatase. placental (Regan isozyme)) reacts with human.
OMIM: 171800; gene. [NCBI / EBI]
Products similar to ALPP antibody:
IgG
 PLAP [8B6] (ready-to-use), IgG
Placental alkaline phosphatase, IgG
Placental alkaline phosphatase antibody (ready-to-use), IgG
PLAP [SP15], IgG
PLACENTAL ALKALINE PHOSPHATASE, IgG
Protein
PLAP Human, Protein
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for ALPP ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| Kimura.K.. (2006) Genome Res. 16 (1). 55-65. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: ALPP antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of ALPP antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about ALPP antibody, all related information, articles, resources about ALPP antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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