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| E2F7 Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-003-44024 |
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| Trial Size Available. Please expect delivery of trial size products to be 4 weeks. |
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| Related Product Names:
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E2F7 antibody; E2F7; A630014C11Rik, D10Ertd739e; E2F7
- E2F-7; E2F transcription factor 7 [Mus musculus]; Transcription factor E2F7 |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: E2F7 |
Gene Name Synonym: A630014C11Rik, D10Ertd739e |
Gi #:
40254337 |
NCBI Acc #:
NP_848724.2 |
Swiss Prot Acc #:
Q6S7F2 |
Length (aa): 904 |
Mol. Weight (Da): 99535 |
Chrom Location: N/A |
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 Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Mouse E2f7.
ELISA Titre: 1:312500
Category: TF for Mouse
Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.
Source/Host: Rabbit
Purity/Purification: Rabbit IgG purified by protein A chromatography.
Clonality: Polyclonal
Crossreactivity: Mouse
Format: Suggested dilution at 2.5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.
Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 microl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.
Stability: Note: Avoid repeat freeze-thaw cycles.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for E2F7 ANTIBODY: |
| WB: Tested |
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| E2F7 ANTIBODY TARGET DESCRIPTION: |
Synonym Names for E2F7 antibody: E2F7; A630014C11Rik, D10Ertd739e; E2F-7; E2F transcription factor 7 [Mus musculus]; Transcription factor E2F7
E2F7 is a E2F family member. It can block the E2F-dependent activation of a subset of E2F target genes as well as mitigate cellular proliferation of mouse embryo fibroblasts.
Function: Inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Modulates the activity of other E2F proteins, such as E2F1, probably by competing or displacing activating E2Fs from promoter binding.
Subunit: Self-associates. Probably binds DNA as a homodimer (By similarity).
Subcellular Location: Nucleus.
Tissue Specificity: Widely expressed with highest levels in skin and thymus and very low levels in brain, muscle and stomach.
Domain: Both DNA-binding domains are required for DNA-binding and are proposed to form an intramolecular structure that is similar to the winged helix structure of the E2F-DP heterodimer (By similarity).
Similarity: Belongs to the E2F/DP family.
E2F7 reacts with mouse.
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for E2F7 ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| de Bruin.A.. et al.. (2003) J. Biol. Chem. 278 (43). 42041-42049. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: E2F7 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of E2F7 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about E2F7 antibody, all related information, articles, resources about E2F7 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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