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ID4 (inhibitor of DNA binding 4. dominant negative helix-loop-helix protein) Antibody, Rabbit Polyclonal Antibody Printer Friendly Datasheet
Catalog Number: 18-003-44061
Buy ID4 antibody - Size:   
  Related Product Names:
- ID4 antibody; ID4; ID4 (inhibitor of DNA binding 4. dominant negative helix-loop-helix protein)
- Inhibitor of DNA binding 4; Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein; DNA-binding protein inhibitor ID-4
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
 Gene Name: ID4  Gene Name Synonym: N/A

 Gi #: 4504573

 NCBI Acc #: NP_001537.1

 Swiss Prot Acc #: P47928

 Length (aa): 161

 Mol. Weight (Da): 16622

 Chrom Location: N/A
 Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human ID4.

 ELISA Titre: 1:1562500

 Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.

 Source/Host: Rabbit

 Purity/Purification: Rabbit IgG purified by protein A chromatography.

 Clonality: Polyclonal

 Crossreactivity: Human, Mouse, Rat, Dog

 Format: Suggested dilution at 1.25 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.

 Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 microl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.

 Stability: Note: Avoid repeat freeze-thaw cycles.

 Shipping: Products may be shipped on ice pack or dry ice.
 APPLICATIONS for ID4 ANTIBODY:
 WB: Tested
 TESTING: (secondary reagents and protocols [IHC Protocol])
 WB: ( anti-ID4 )

ID4 antibody WB image
ID4

 ID4 ANTIBODY TARGET DESCRIPTION:
Synonym Names for ID4 antibody: ID4; Inhibitor of DNA binding 4; Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein; DNA-binding protein inhibitor ID-4

Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodime

Function: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding.

Subunit: Heterodimer with other HLH proteins.

Subcellular Location: Nucleus.

Similarity: Contains 1 basic helix-loop-helix (bHLH) domain.

Summary: Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995 [PubMed 7665172]).[supplied by OMIM].

ID4 (inhibitor of DNA binding 4. dominant negative helix-loop-helix protein) reacts with human, mouse, rat, dog.

OMIM: 600581; gene. [NCBI / EBI]

Products similar to ID4 antibody:
 IgG
    DPF2 (D4. zinc and double PHD fingers family 2), IgG
    D4 GDI, IgG
    Rabbit anti BRCAA1, IgG
    D4 GDI (ready-to-use), IgG
    D4 GDI [97A1015], IgG
 Protein
    D4GDI Human, Protein
SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
 BACKGROUND REFERENCES for ID4 ANTIBODY:
Background references for antibody target are not specific to GenWay products
Yu.L.. et al.. (2005) Nat. Genet. 37 (3). 265-274.
Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: ID4 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of ID4 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about ID4 antibody, all related information, articles, resources about ID4 antibody are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

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