Alphabetical Listing of Primary Antibodies:
f
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0-4
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5-9
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A
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B
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C
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D
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E
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F
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G
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H
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I
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J
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K
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L
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M
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N
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O
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P
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Q
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R
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S
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T
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U
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V
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W
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X
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Y
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Z
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Alphabetical Listing of Proteins:
f
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0-4
|
5-9
|
A
|
B
|
C
|
D
|
E
|
F
|
G
|
H
|
I
|
J
|
K
|
L
|
M
|
N
|
O
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P
|
Q
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R
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S
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T
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U
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V
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W
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X
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Y
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Z
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Peptides
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Secondary Antibodies
|
ELISA Kits
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast)) Antibody, Rabbit Polyclonal Antibody
Catalog Number: 18-003-44758
Buy UBE2I antibody -
Size:
0.1 mg ($255.00)
Related Product Names:
- UBE2I antibody; UBE2I; UBC9; UBCE9; UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
- EC 6.3.2.-; SUMO-protein ligase; Ubiquitin-conjugating enzyme E2 I; Ubiquitin-protein ligase I; Ubiquitin carrier protein I; Ubiquitin carrier protein 9; p18; Ubiquitin-conjugating enzyme E2I; SUMO-conjugating enzyme UBC9
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact
sales@genwaybio.com
.
Gene Name:
UBE2I
Gene Name Synonym:
UBC9; UBCE9
Gi #:
4507785
NCBI Acc #:
NP_003336.1
Swiss Prot Acc #:
P63279
Length (aa):
158
Mol. Weight (Da):
18007
Chrom Location:
N/A
Antigen Specificity:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human UBE2I.
ELISA Titre:
1:312500
Note:
Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.
Source/Host:
Rabbit
Purity/Purification:
Rabbit IgG purified by protein A chromatography.
Clonality:
Polyclonal
Crossreactivity:
Human, Mouse, Rat, Dog, Zebra Fish
Format:
Suggested dilution at 2.5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.
Storage:
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.
Stability:
Note: Avoid repeat freeze-thaw cycles.
Shipping:
Products may be shipped on ice pack or dry ice.
APPLICATIONS for UBE2I ANTIBODY:
WB: Tested
TESTING: (
secondary reagents
and
protocols
[IHC Protocol]
)
WB:
( anti-UBE2I )
UBE2I antibody WB image
UBE2I ANTIBODY TARGET DESCRIPTION:
Synonym Names for UBE2I antibody:
UBE2I; UBC9; UBCE9; EC 6.3.2.-; SUMO-protein ligase; Ubiquitin-conjugating enzyme E2 I; Ubiquitin-protein ligase I; Ubiquitin carrier protein I; Ubiquitin carrier protein 9; p18; Ubiquitin-conjugating enzyme E2I; SUMO-conjugating enzyme UBC9
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes. or E1s. ubiquitin-conju
Function:
Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Essential for nuclear architecture and chromosome segregation.
Catalytic Activity:
ATP + SUMO + protein lysine = AMP + diphosphate + protein N-SUMOyllysine.
Pathway:
SUMO conjugation; second step.
Subunit:
Interacts with HIPK1, HIPK2 and PPM1J (By similarity). Forms a tight complex with RANGAP1 and RANBP2. Interacts with SIAH1 and PARP. Interacts with various transcription factors such as TCF3, TFAP2A, TFAP2B, TFAP2C, AR, ETS1 and SOX4.. Interacts with human adenovirus E1A and human herpesvirus 6 IE2.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in heart, skeletal muscle, pancreas, kidney, liver, lung, placenta and brain. Also expressed in testis and thymus.
Similarity:
Belongs to the ubiquitin-conjugating enzyme family.
Summary:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This protein is a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast)) reacts with human, mouse, rat, dog, zebra fish.
OMIM:
601661; gene. [
NCBI
/
EBI
]
Products similar to UBE2I antibody:
IgG
UBE2I, IgG
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast)), IgG
UBE2I, IgG
UbC9 Human, Protein
Ubc9 (Human ubiquitin conjugating enzyme 9), Protein
PRODUCT INTERACTIONS:
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
BHLHB2 (basic helix-loop-helix domain containing. class B. 2), IgG
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
SHARP2, IgG
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
HNRPD, IgG
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
HNRPD, IgG
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
Anti-SUMO Activating Enzyme E1, IgG
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
SUMO-I Human, Protein
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
SUMO-1, IgG
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
SUMO-1, IgG
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
Anti-SUMO (Yeast), IgG
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
Anti-SUMO, IgG
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
TFAP2C (transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)), IgG
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
AP2 gamma [AP2g 6E4/4], IgG
(GenWay Catalog #: 18-003-44758)
.
UBE2I (ubiquitin-conjugating enzyme E2I (UBC9 homolog. yeast))
interacts
with
Rabbit anti UBE1, IgG
(GenWay Catalog #: 18-003-44758)
.
SUGGESTED ANITBODY REAGENTS
- GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
BACKGROUND REFERENCES for UBE2I ANTIBODY:
Background references for antibody target are not specific to GenWay products
Zhu.S.. (2006) Exp. Cell Res. 312 (7). 1042-1049.
Order Confirmation:
Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions:
UBE2I antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes:
During shipment, small volumes of UBE2I antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright:
This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about UBE2I antibody, all related information, articles, resources about UBE2I antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer:
For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.
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