Il17a protein, IL-17 Mouse recombinant protein

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IL-17 Mouse recombinant protein

Catalog Number: 10-663-45207

Buy Il17a protein -

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Related Product Names:

- Il17a protein; Il17a; Ctla8; Il17; IL-17 Mouse
- CTLA-8, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8.; IL-17A; IL-17; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8; interleukin-17A [Mus musculus]

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: Il17a	Gene Name Synonym: Ctla8; Il17
Gi #: N/A	NCBI Acc #: N/A	Swiss Prot Acc #: Q62386
Length (aa): N/A	Mol. Weight (Da): 17490	Chrom Location: N/A

Amino Acid Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be, Ala-Ala-Ile-Ile-Pro.

Biological Activity: The ED50 as determined by the dose-dependant secretion of IL-6 by NIH 3T3 cells was found to be 1.0-10.0 ng/mL.

Protein Content: Protein quantitation was carried out by two independent methods:
1. UV spectroscopy at 280 nm using the absorbency value of 0.942 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics).
2. Analysis by RP-HPLC, using a standard solution of IL-17 as a Reference Standard.

Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.

Solubility: It is recommended to reconstitute the lyophilized Interleukin 17 in sterile 18MO-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Source/Host: E. Coli

Purity/Purification: Greater than 95.0% as determined by (a)Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Format: Lyophilized from a concentrated solution containing no additives.

Stability: Lyophilized Interleukin-17 although stable at room temperature for 3 weeks, should be stored desiccated below -18 C. Upon reconstitution IL17 should be stored at 4 C between 2-7 days and for future use below -18 C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Shipping: Products may be shipped on ice pack or dry ice.

TESTING: (secondary reagents and protocols )

Not Available

IL17A PROTEIN TARGET DESCRIPTION:

Synonym Names for Il17a protein: Il17a; Ctla8; Il17; CTLA-8, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8.; IL-17A; IL-17; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8; interleukin-17A [Mus musculus]

Interleukin-17 Murine Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 266 amino acids and having a molecular mass of 29,956 Dalton.
The IL-17 is purified by proprietary chromatographic techniques.

IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Function: Induces stromal cells to produce proinflammatory and hematopoietic cytokines (By similarity).

Subunit: Homodimer (By similarity).

Subcellular Location: Secreted.

Tissue Specificity: Restricted to a subset of activated T-cells.

Similarity: Belongs to the IL-17 family.

Products similar to Il17a protein:

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IL17, IgG

IL-17, IgG

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Rabbit anti Human IL-17, IgG

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Mouse IL-17,, Protein

Interleukin-17A, Protein

IL-17 Human, Protein

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Precautions: Il17a protein is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of Il17a protein vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about Il17a protein, all related information, articles, resources about Il17a protein are being stored on our online database. Let us know if you have questions regarding this product.

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