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HSP90 Alpha Human recombinant protein Printer Friendly Datasheet
Catalog Number: 10-663-45497
Buy HSP90AA1 protein - Size:   
  Related Product Names:
- HSP90AA1 protein; HSP90AA1; HSP90A; HSPC1; HSPCA; HSP90 Alpha Human
- HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, HSP90A, HSP90N, HSPCAL1, HSPCAL4, FLJ31884.; HSP 86; Renal carcinoma antigen NY-REN-38; Heat shock protein HSP 90-alpha
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
 Gene Name: HSP90AA1  Gene Name Synonym: HSP90A; HSPC1; HSPCA

 Gi #: N/A

 NCBI Acc #: NP_001017963.2

 Swiss Prot Acc #: P07900

 Length (aa): N/A

 Mol. Weight (Da): 84660

 Chrom Location: N/A
 Physical Appearance: Sterile filtered colorless solution.

 Source/Host: Escherichia Coli.

 Purity/Purification: Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

 Format: The HSP90 protein solution (1mg/ml) contains 20mM Tris-HCl, pH-7.4 and 100mM NaCl.

 Stability: Store at 4 C if entire vial will be used within 2-4 weeks. Store, frozen at -20 C for longer periods of time. Avoid multiple freeze-thaw cycles For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

 Shipping: Products may be shipped on ice pack or dry ice.
 TESTING: (secondary reagents and protocols )
 Not Available
 HSP90AA1 PROTEIN TARGET DESCRIPTION:
Synonym Names for HSP90AA1 protein: HSP90AA1; HSP90A; HSPC1; HSPCA; HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, HSP90A, HSP90N, HSPCAL1, HSPCAL4, FLJ31884.; HSP 86; Renal carcinoma antigen NY-REN-38; Heat shock protein HSP 90-alpha

Recombinant HSP-90 produced in E.Coli is a single,non-glycosylated polypeptide chain containing 732 amino acids and having a molecular mass of 86.8kDa.
HSP90 is expressed with a 6xHis tag and purified by proprietary chromatographic techniques

HSP90 has been identified in the cytosol, nucleus and endoplasmic reticulum, and is reported to exist in many tissue types. In several tissues, including smooth muscle, HSP90 comprises up to 2% of total cellular protein. HSP90 functions as a dimer, assembled as part of heterocomplex. It possesses ATP-binding site and low ATPase activity. HSP90 is able to associate with actin filaments in certain conditions. Another important property of HSP90 is the binding of unoccupied steroid hormone receptors. HSP90 has been characterized as a molecular chaperone able to keep the target protein in a folding-competent state. It has an enhanced chaperone activity in oligomeric form at high temperatures. HSP90 function is sensitive to bivalent cations concentration.

Function: Molecular chaperone. Has ATPase activity (By similarity).

Subunit: Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.

Subcellular Location: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Similarity: Belongs to the heat shock protein 90 family.

OMIM: 140571; gene. [NCBI / EBI]

Pathways:
KEGG pathway: Antigen processing and presentation 04612
KEGG pathway: Prostate cancer 05215
Reactome Event:Metabolism of nitric oxide 202131

Products similar to HSP90AA1 protein:
 IgG
    FXYD5 (FXYD domain containing ion transport regulator 5), IgG
    CNOT2 (CCR4-NOT transcription complex. subunit 2), IgG
    Hsp90 [S88], IgG
    HEAT SHOCK PROTEIN 90 BETA, IgG
    Protein Kinase D2 antibody, IgG
 Protein
    HSP 90, Protein
    HSPC139, Protein
    Zinc finger protein 581, Protein
    HSPC142 protein, Protein
 PRODUCT INTERACTIONS:
 HSP90 Alpha Human interacts with U6 snRNA-associated Sm-like protein LSm1, Protein (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with MMP2, IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with MMP2, IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with Sheep anti MMP-2, IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with Rabbit anti MMP-2, Whole Molecule, IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with MMP2, IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with MMP2, IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with MMP2, IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with MMP2, IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with MMP2, IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with MMP2, IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with MMP-2, IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with NDRG1 (N-myc downstream regulated gene 1), IgG (GenWay Catalog #: 10-663-45497).
 HSP90 Alpha Human interacts with NDRG1 (N-myc downstream regulated gene 1), IgG (GenWay Catalog #: 10-663-45497).
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: HSP90AA1 protein is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of HSP90AA1 protein vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about HSP90AA1 protein, all related information, articles, resources about HSP90AA1 protein are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

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