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p53 Human recombinant protein Printer Friendly Datasheet
Catalog Number: 10-663-45596
Buy TP53 protein - Size:   
  Related Product Names:
- TP53 protein; TP53; P53; p53 Human
- p53 Protein Human Recombinant; Tumor suppressor p53; Phosphoprotein p53; Antigen NY-CO-13; Cellular tumor antigen p53
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
 Gene Name: TP53  Gene Name Synonym: P53

 Gi #: N/A

 NCBI Acc #: NP_000537.3

 Swiss Prot Acc #: P04637

 Length (aa): N/A

 Mol. Weight (Da): 43712

 Chrom Location: N/A
 Physical Appearance: Sterile Filtered clear solution.

 Activity: p53 is active in DNA binding assays. It can be used as a reagent for development of DNA based binding Assay.

 Presentation: 5ug/5ul purified human p53 in 20mM Tris-Acetate, pH 8, 0.6M Nacl and 50% Glycerol.

 Useful Applications: P53 is an excellent substrate for kinase assays
· It can be used as a reagent for development of DNA based binding Assay.

 Source/Host: E. Coli

 Purity/Purification: Greater than 95.0% as determined by SDS-PAGE.

 Format: Purified human p53 in 20mM Tris, pH 8, 0.6M Nacl and 50% Glycerol.

 Stability: For long term storage store at -20°C. Avoid freeze/thaw cycles.

 Shipping: Products may be shipped on ice pack or dry ice.
 TESTING: (secondary reagents and protocols )
 Not Available
 TP53 PROTEIN TARGET DESCRIPTION:
Synonym Names for TP53 protein: TP53; P53; p53 Protein Human Recombinant; Tumor suppressor p53; Phosphoprotein p53; Antigen NY-CO-13; Cellular tumor antigen p53

Tumor protein p53 responds to various cellular stresses by regulating target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. p53 is a DNA-binding protein containing transcription activation, DNA-binding & oligomerization domains. p53 binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. p53 protein is a transcription factor which is encoded in humans by the TP53 gene. Alterations of TP53 occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome. p53 mutants that often occur in many different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma. The p53 expression in normal cells is low and in an assortment of transformed cell lines is high, which may contribute to transformation and malignancy. Multiple p53 variants encode distinct isoforms, which can regulate p53 transcriptional activity. p53’s significance in multicellular organisms is in cell cycle regulation therefore it functions as a tumor suppressor that is involved in preventing cancer. p53’s role in conserving stability by preventing genome mutation has earned it descriptions such as "the guardian of the genome," "the guardian angel gene," and the "master watchman.” The name p53 refers to its evident molecular mass: it migrates as a 53kDa protein on SDS-PAGE. However, based on calculations from its amino acid residues, p53's mass is in fact only 43.7kDa. This difference is attributed to the high number of proline residues in the protein which slow its migration on SDS-PAGE, consequently making it appear larger than it actually is.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Function: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.

Cofactor: Binds 1 zinc ion per subunit.

Subunit: Interacts with AXIN1. Probably part of a complex consisting of TP53, HIPK2 and AXIN1 (By similarity). Binds DNA as a homotetramer. Interacts with histone acetyltransferases EP300 and methyltransferases HRMT1L2 and CARM1, and recruits them to promoters. In vitro, the interaction of TP53 with cancer-associated/HPV (E6) viral proteins leads to ubiquitination and degradation of TP53 giving a possible model for cell growth regulation. This complex formation requires an additional factor, E6-AP, which stably associates with TP53 in the presence of E6. C-terminus interacts with TAF1, when TAF1 is part of the TFIID complex. Interacts with ING4 and this interaction may be indirect. Found in a complex with CABLES1 and TP73. Interacts with HIPK1, HIPK2, and P53DINP1. Interacts with WWOX. May interacts with HCV core protein. Interacts with USP7 and SYVN1. Interacts with HSP90AB1 (By similarity). Interacts with ARMC10, BANP, CDKN2AIP and E4F1.

Subcellular Location: Cytoplasm. Nucleus. Endoplasmic reticulum. Note=Interaction with BANP promotes nuclear localization.

Domain: The nuclear export signal acts as a transcriptional repression domain.

Ptm: Acetylated. Acetylation of Lys-382 by CREBBP enhances transcriptional activity. Deacetylation of Lys-382 by SIRT1 impairs its ability to induce proapoptotic program and modulate cell senescence.

Ptm: Phosphorylation on Ser residues mediates transcriptional activation. Phosphorylated by HIPK1 (By similarity). Phosphorylation at Ser-9 by HIPK4 increases repression activity on BIRC5 promoter. Phosphorylated on Thr-18 by VRK1, which may prevent the interaction with MDM2. Phosphorylated on Thr-55 by TAF1, which promotes MDM2-mediated degradation. Phosphorylated on Ser-46 by HIPK2 upon UV irradiation. Phosphorylation on Ser-46 is required for acetylation by CREBBP. Phosphorylated on Ser-392 following UV but not gamma irradiation. Phosphorylated upon DNA damage, probably by ATM or ATR. Phosphorylated on Ser-15 upon ultraviolet irradiation; which is enhanced by interaction with BANP.

Ptm: Dephosphorylated by PP2A. SV40 small T antigen inhibits the dephosphorylation by the AC form of PP2A.

Ptm: May be O-glycosylated in the C-terminal basic region. Studied in EB-1 cell line.

Ptm: Ubiquitinated by SYVN1, which leads to proteasomal degradation.

Ptm: Monomethylated at Lys-372 by SETD7, leading to stabilize it and increase transcriptional activation. Monomethylated at Lys-370 by SMYD2, leading to decrease DNA-binding activity and subsequent transcriptional regulation activity. Lys-372 monomethylation prevents the interaction with SMYD2 and subsequenct monomethylation at Lys-370.

Disease: TP53 is found in increased amounts in a wide variety of transformed cells. TP53 is frequently mutated or inactivated in about 60% of cancers.

Disease: Defects in TP53 are involved in esophageal squamous cell carcinoma (ESCC) [MIM:133239]. ESCC is a tumor of the esophagus.

Disease: Defects in TP53 are a cause of Li-Fraumeni syndrome (LFS) [MIM:151623]. LFS is an autosomal dominant familial cancer syndrome that in its classic form is defined by the existence of a proband affected by a sarcoma before 45 years with a first degree relative affected by any tumor before 45 years and another first degree relative with any tumor before 45 years or a sarcoma at any age. Other clinical definitions for LFS have been proposed (PubMed:8118819 and PubMed:8718514) and called Li-Fraumeni like syndrome (LFL). In these families affected relatives develop a diverse set of malignancies at unusually early ages. Four types of cancers account for 80% of tumors occurring in TP53 germline mutation carriers: breast cancers, soft tissue and bone sarcomas, brain tumors (astrocytomas) and adrenocortical carcinomas. Less frequent tumors include choroid plexus carcinoma or papilloma before the age of 15, rhabdomyosarcoma before the age of 5, leukemia, Wilms tumor, malignant phyllodes tumor, colorectal and gastric cancers.

Disease: Defects in TP53 may be associated with nasopharyngeal carcinoma [MIM:161550]; also known as nasopharyngeal cancer.

Disease: Defects in TP53 are found in Barrett metaplasia; also known as Barrett esophagus. It is a condition in which the normally stratified squamous epithelium of the lower esophagus is replaced by a metaplastic columnar epithelium. The condition develops as a complication in approximately 10% of patients with chronic gastroesophageal reflux disease and predisposes to the development of esophageal adenocarcinoma.

Disease: Defects in TP53 are involved in head and neck squamous cell carcinomas (HNSCC) [MIM:275355].

Disease: Defects in TP53 are involved in oral squamous cell carcinoma (OSCC). Cigarette smoke is a prime mutagenic agent in cancer of the aerodigestive tract.

Disease: Defects in TP53 are a cause of lung cancer [MIM:211980].

Disease: Defects in TP53 are a cause of choroid plexus papilloma [MIM:260500]. Choroid plexus papilloma is a slow-growing benign tumor of the choroid plexus that often invades the leptomeninges. In children it is usually in a lateral ventricle but in adults it is more often in the fourth ventricle. Hydrocephalus is common, either from obstruction or from tumor secretion of cerebrospinal fluid. If it undergoes malignant transformation it is called a choroid plexus carcinoma. Primary choroid plexus tumors are rare and usually occur in early childhood.

Disease: Defects in TP53 are a cause of one form of hereditary adrenocortical carcinoma (ADCC) [MIM:202300]. ADCC is a rare childhood tumor, representing about 0.4% of childhood tumors, with a high incidence of associated tumors. ADCC occurs with increased frequency in patients with the Beckwith-Wiedemann syndrome [MIM:130650] and is a component tumor in Li-Fraumeni syndrome [MIM:151623].

Similarity: Belongs to the p53 family.

OMIM: 133239; phenotype. [NCBI / EBI]
151623; phenotype. [NCBI / EBI]
161550; phenotype. [NCBI / EBI]
191170; gene+phenotype. [NCBI / EBI]
202300; phenotype. [NCBI / EBI]
211980; phenotype. [NCBI / EBI]
260500; phenotype. [NCBI / EBI]
275355; phenotype. [NCBI / EBI]

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 PRODUCT INTERACTIONS:
 p53 Human interacts with SV40 T-antigen [PAb416], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with ATR [2B5], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with ATR [2B5], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with ATR, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with ATR, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with BARD1, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Cytoplasmic tyrosine-protein kinase BMX, Protein (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with CEBPB [1H7], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with CEBPB (CCAAT/enhancer binding protein (C/EBP). beta), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with NFIL6 [21A1], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with NFIL6 [21A1], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with CREB BINDING PROTEIN, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with CREB BINDING PROTEIN, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with CBP, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with CBP, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Rabbit anti Cul7 (a.a. 1679-1698), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Anti-Human Cul7 (C-terminal specific), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Anti-CULLIN7 (Rabbit), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with DAXX, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with DAXX, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with DAXX [DAXX-01], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with DAXX, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with p300 [3G230], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with p300, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with p300, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with HDAC1 (histone deacetylase 1), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with HDAC1 [HDAC1-21], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Anti-HDAC-1, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with HDAC1, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with HDAC1 (ready-to-use), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with HDAC1, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with HMGB1 [HAP46.5], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with HMGB1 Human, Protein (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with MYST, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Huntingtin, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Huntingtin (a.a. 1844-2131), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Huntingtin (a.a. 2703-2911), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Huntingtin (a.a. 997-1276), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Anti-Huntington pS421, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with HUNTINGTIN, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with HUNTINGTIN, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with HUNTINGTIN, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Mitogen-activated protein kinase 11, Protein (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with MDM2 [2A10], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with MDM2 [SMP14], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with MDM2 [SMP14], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Rabbit anti Mouse MDM2 pS185, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with MDM2 [HDM2-323], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with MDM2 [MD-219], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with MDM2 (ready-to-use), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with MDM4 (Mdm4. transformed 3T3 cell double minute 4. p53 binding protein (mouse)), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with MDM4 (Mdm4. transformed 3T3 cell double minute 4. p53 binding protein (mouse)), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with NFYA (nuclear transcription factor Y. alpha), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with NFYA (nuclear transcription factor Y. alpha), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Anti-NF-Y (A subunit) (Rabbit), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with NFY, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Nucleophosmin [NA24], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Nucleophosmin [FC82291], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Rabbit anti PARC (a.a. 2503-2517), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Anti-Human PARC (C-terminal specific), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PARP cleaved [194C1439], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PARP [10H], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PARP cleaved, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PARP cleaved, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PARP1 (poly (ADP-ribose) polymerase family. member 1), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with POLY(ADP-RIBOSE) POLYMERASE, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PARP cleaved, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PARP cleaved (FITC), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PARP cleaved, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PARP (ready-to-use), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PIAS4 (protein inhibitor of activated STAT. 4), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PAIAS gamma, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK1 Human, Protein (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK phospho Y576, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK phospho Y407, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK phospho Y861, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK phospho Y577, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK phospho S910, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK phospho S732, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK (Phospho-Tyr861), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK (Phospho-Tyr925), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK (Ab-861), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK (Ab-925), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK (Phospho-Tyr861) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK (Phospho-Tyr925) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Pyk2 (Phospho-Tyr402) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PYK2 phospho Y579, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PYK2 phospho Y579, Y580, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK phospho Y397, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PYK2 phospho Y881, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with PYK2 phospho Y402, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with FAK phospho S722, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Rad51 [14B4], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Rad51 [13E4], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Rad51 [14B4], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with replication protein A1, 70kDa (RPA1), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with RPA70, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with RPA70, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Peripherin, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ubiquitin Human, Protein (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ubiquitin K48R Human, Protein (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ubiquitin Human, Protein (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ubiquitin G76A Human, Protein (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ubiquitin, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ubiquitin (ready-to-use), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ubiquitin [Ubi-1], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ubiquitin (a.a. 50-65), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ubiquitin (a.a. 64-76), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Rabbit A' Ubiquitin, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Anti-UBIQUITIN, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ubiquitin (ready-to-use), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ubiquitin, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with ubiquitin [1B4-UB], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with SET7/9 Histone methyltransferase, Protein (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with HMTase Human, Protein (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with SET 7/9 (clone s4E5), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with TATA box binding protein, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with TATA binding protein TBP [1TB18], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with TATA binding protein TBP [1TBP18], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with TBP (TATA box binding protein), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with TATA-Binding Protein, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with TP53BP2 (tumor protein p53 binding protein. 2), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with UBE3A, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with E6AP, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with UBE3A, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with WRN, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ku P70/P80 Human, Protein (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ku70, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ku70 [1.5], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ku70 + Ku80 [162], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ku70, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ku70, IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ku70 [529], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with Ku70 [1.5], IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with ZNF385 (zinc finger protein 385), IgG (GenWay Catalog #: 10-663-45596).
 p53 Human interacts with ZNF385 (zinc finger protein 385), IgG (GenWay Catalog #: 10-663-45596).
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Precautions: TP53 protein is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of TP53 protein vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about TP53 protein, all related information, articles, resources about TP53 protein are being stored on our online database. Let us know if you have questions regarding this product.

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