Ambp native protein, UTI Human native protein

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UTI Human native protein

Catalog Number: 11-663-46067

Buy Ambp native protein -

Size:

Trial Size Available

Related Product Names:

- Ambp native protein; Ambp; Itil; UTI Human
- Urinary Trypsin Inhibitor-Ulinastatin Human; N/A; Protein AMBP

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: Ambp	Gene Name Synonym: Itil
Gi #: N/A	NCBI Acc #: N/A	Swiss Prot Acc #: Q07456
Length (aa): N/A	Mol. Weight (Da): 39029	Chrom Location: N/A

Biological Activity: HuUTI has an activity of 1000IU/mg.

Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.

Solubility: It is recommended to reconstitute the lyophilized HuUTI in sterile 18M-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Source/Host: Hu Urine.

Purity/Purification: Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Anion-exchange FPLC.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.

Format: Lyophilized from a (1mg/ml) solution containing no additives.

Stability: Lyophilized HuUTI although stable at room temperature for 3 weeks, should be stored desiccated below -18 C. Upon reconstitution HuUTI should be stored at 4 C between 2-7 days and for future use below -18 C.
Please prevent freeze-thaw cycles.

Shipping: Products may be shipped on ice pack or dry ice.

TESTING: (secondary reagents and protocols )

Not Available

AMBP NATIVE PROTEIN TARGET DESCRIPTION:

Synonym Names for Ambp native protein: Ambp; Itil; Urinary Trypsin Inhibitor-Ulinastatin Human; N/A; Protein AMBP

Urinary Trypsin Inhibitor (UTI, Ulinastatin) is a kind of glucoprotein derived from human urine. As a proteinase inhibitor, it inhibits the activity of trypsin, chymotrypsin, lactate, lipase, hyaluronidase and other pancreatic enzymes. UTI is an effective for acute pancreatitis, chronic recurrent pancreatitis and hemorrhagic, traumatic and endotoxic shocks. UTI is has strong inhibition effect to various protease, sugar and fat hydrolase.

Function: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization (By similarity).

Function: Trypstatin is a trypsin inhibitor (By similarity).

Subunit: I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin. Alpha-1-microglobulin occurs as a monomer and also in complexes with IgA and albumin. Alpha-1-microglobulin interacts with FN1. Trypstatin is a monomer and also occurs as a complex with tryptase in mast cells (By similarity).

Subcellular Location: Secreted.

Tissue Specificity: Expressed by the liver and secreted in plasma. Alpha-1-microglobulin occurs in many physiological fluids including plasma, urine, and cerebrospinal fluid. Inter-alpha-trypsin inhibitor is present in plasma and urine.

Ptm: The precursor is proteolytically processed into separately functioning proteins.

Ptm: 3-hydroxykynurenine, an oxidized tryptophan metabolite that is common in biological fluids, reacts with Cys-52, Lys-110, Lys-136, and Lys-148 to form heterogeneous polycyclic chromophores including hydroxanthommatin. The reaction by alpha-1-microglobulin is autocatalytic. The chromophore can react with accessible cysteines forming non-reducible thioether cross-links with other molecules of alpha-1-microglobulin or with other proteins such as Ig alpha-1 chain C region (By similarity).

Ptm: Heavy chains are interlinked with bikunin via a chondroitin 4-sulfate bridge to the their C-terminal aspartate (By similarity).

Similarity: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.

Similarity: Contains 2 BPTI/Kunitz inhibitor domains.

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IgG

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ALPHA 1 MICROGLOBULIN, IgG

Rabbit anti Alpha 1 Microglobulin, IgG

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Precautions: Ambp native protein is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of Ambp native protein vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about Ambp native protein, all related information, articles, resources about Ambp native protein are being stored on our online database. Let us know if you have questions regarding this product.

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