CIRBP protein, Cold-inducible RNA-binding protein recombinant protein

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Cold-inducible RNA-binding protein recombinant protein

Catalog Number: 10-288-22013F

Buy CIRBP protein -

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Related Product Names:

- CIRBP protein; CIRBP; A18HNRNP; CIRP; Cold-inducible RNA-binding protein
- Glycine-rich RNA-binding protein CIRP; A18 hnRNP; Cold inducible RNA binding protein

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: CIRBP	Gene Name Synonym: A18HNRNP; CIRP
Gi #: 4502847	NCBI Acc #: NP_001271.1	Swiss Prot Acc #: Q14011
Length (aa): 172	Mol. Weight (Da): 18648	Chrom Location: 19p13.3

Linear Protein Map of Expressed Protein (sequence source from above GI#)

Fusion: His-Tag at N-terminus.

Source/Host: E Coli

Purity/Purification: 95%

Crossreactivity: human

Format: 10 mM Tris, pH 8.0, 0.002% NaN3, 3mM NaCl, 2.5mM Imidazole.

Storage: -70 degree C. Avoid frequent freeze and thaw.

Stability: 6-12 months at -70 degree C.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for CIRBP PROTEIN:

MS, SDS: Tested

ELISA, Western Blot: Not Tested

TESTING: (secondary reagents and protocols )

SDS: Analysis of CIRBP Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining. ( anti-CIRBP protein )

CIRBP protein SDS image
CIRBP

CIRBP PROTEIN TARGET DESCRIPTION:

Synonym Names for CIRBP protein: CIRBP; A18HNRNP; CIRP; Glycine-rich RNA-binding protein CIRP; A18 hnRNP; Cold inducible RNA binding protein

Function: Seems to play an essential role in cold-induced suppression of cell proliferation.

Subcellular Location: Nucleus; nucleoplasm (By similarity).

Tissue Specificity: Ubiquitous.

Induction: By cold stress an in response to DNA damage induced by UV irradiation or UV mimetic agents.

Similarity: Contains 1 RRM (RNA recognition motif) domain.

Cold-inducible RNA-binding protein reacts with human.

OMIM: 602649; gene. [NCBI / EBI]

SUGGESTED PROTEIN REAGENTS - GenWay offers reagents to facilitate your research with cell-based assays, Mass Spectrometry, standards, calibrators, Western blot, cell culture, antibiotics, microwell substrates, and more!

BACKGROUND REFERENCES for CIRBP PROTEIN:

Background references for antibody target are not specific to GenWay products

[1] Wellmann,S., Buhrer,C., Moderegger,E., Zelmer,A., Kirschner,R., Koehne,P., Fujita,J. and Seeger,K.
     Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism
[2] Hamid,A.A., Mandai,M., Fujita,J., Nanbu,K., Kariya,M., Kusakari,T., Fukuhara,K. and Fujii,S.
     Expression of cold-inducible RNA-binding protein in the normal endometrium, endometrial hyperplasia, and endometrial carcinoma
[3] Lee,J. and Bedford,M.T., et al.
     PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays
[4] Nishiyama,H., Danno,S., Kaneko,Y., Itoh,K., Yokoi,H., Fukumoto,M., Okuno,H., Millan,J.L., Matsuda,T., Yoshida,O. and Fujita,J.
     Decreased expression of cold-inducible RNA-binding protein (CIRP) in male germ cells at elevated temperature
[5] Nishiyama,H., Higashitsuji,H., Yokoi,H., Itoh,K., Danno,S., Matsuda,T. and Fujita,J.
     Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene
[6] , Nishiyama H., Higashitsuji H., Yokoi H., Itoh K., Danno S., Matsuda T., Fujita J.
     Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene.
[7] , Sheikh M.S., Carrier F., Papathanasiou M.A., Hollander M.C., Zhan Q., Yu K., Fornace A.J. Jr.
     Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein.
[8] , Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., et al.
     The DNA sequence and biology of human chromosome 19.
[9] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
     Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: CIRBP protein is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of CIRBP protein vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about CIRBP protein, all related information, articles, resources about CIRBP protein are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

SERVICES AVAILABLE for CIRBP PROTEIN:

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