YWHAZ protein, 14-3-3 protein zeta/delta recombinant protein

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Peptides \| Secondary Antibodies \| ELISA Kits

14-3-3 protein zeta/delta recombinant protein

Catalog Number: 10-288-22342F

Buy YWHAZ protein -

Size:

Related Product Names:

- YWHAZ protein; YWHAZ; KCIP-1; MGC111427; MGC126532; MGC138156; 14-3-3 protein zeta/delta
- Protein kinase C inhibitor protein 1; KCIP-1; Tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: YWHAZ	Gene Name Synonym: KCIP-1; MGC111427; MGC126532; MGC138156
Gi #: 4507953	NCBI Acc #: NP_003397.1	Swiss Prot Acc #: P63104
Length (aa): 245	Mol. Weight (Da): 27745	Chrom Location: 8q23.1

Linear Protein Map of Expressed Protein (sequence source from above GI#)

Fusion: His-Tag at N-terminus.

Source/Host: E Coli

Purity/Purification: 95%

Crossreactivity: human

Format: 10 mM Tris, pH 8.0, 0.002% NaN3, 3mM NaCl, 2.5mM Imidazole.

Storage: -70 degree C. Avoid frequent freeze and thaw.

Stability: 6-12 months at -70 degree C.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for YWHAZ PROTEIN:

MS, SDS: Tested

ELISA, Western Blot: Not Tested

TESTING: (secondary reagents and protocols )

SDS: Analysis of YWHAZ Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining. ( anti-YWHAZ protein )

YWHAZ protein SDS image
YWHAZ

YWHAZ PROTEIN TARGET DESCRIPTION:

Synonym Names for YWHAZ protein: YWHAZ; KCIP-1; MGC111427; MGC126532; MGC138156; Protein kinase C inhibitor protein 1; KCIP-1; Tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide

Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Subunit: Homodimer. Interacts with PCTK1. Binds to the C-terminal part of WEE1. Interacts with BSPRY (By similarity). Interacts with SSH1.

Subcellular Location: Cytoplasm.

Ptm: Isoform delta differs from isoform zeta in being phosphorylated (By similarity).

Similarity: Belongs to the 14-3-3 family.

Summary: This protein product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.

14-3-3 protein zeta/delta reacts with human.

OMIM: 601288; gene. [NCBI / EBI]

Pathways:
KEGG pathway: Cell cycle 04110
KEGG pathway: Pathogenic Escherichia coli infection - EHEC 05130
KEGG pathway: Pathogenic Escherichia coli infection - EPEC 05131

Products similar to YWHAZ protein:

IgG

YWHAB, IgG

14-3-3 beta + zeta [4E2], IgG

14-3-3 beta (ready-to-use), IgG

14-3-3 beta [4E1], IgG

14-3-3 beta, IgG

Protein

14-3-3 protein epsilon, Protein

PRODUCT INTERACTIONS:

14-3-3 protein zeta/delta interacts with c-Abl phospho Y245, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with c-Abl (Phospho-Tyr412), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with c-Abl (Ab-412), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with c-Abl (Phospho-Tyr412) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with Herpes Type 6 p150, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with c-Abl (ready-to-use), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with c-Abl, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with c-Abl [19-110], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with c-Abl [ABL-148], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with c-Abl phospho Y412, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with c-Abl, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with cofilin (Phospho-Ser3), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with cofilin (Ab-3), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with cofilin (Phospho-Ser3) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with CFL1 Human, Protein (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with Cofilin (phospho S3), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with Cofilin, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGF R, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (ready-to-use), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [ICR10], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [Cocktail R19/48 (111.6 + 199.12 + F4 + 11E8)], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [199.12], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [2E9], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with Acitve EGF Receptor EIA Kit, ELISA_Kits (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Phospho-Ser1070), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Phospho-Tyr1092), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Phospho-Thr678), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Phospho-Thr693), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Phospho-Tyr1172), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Phospho-Tyr1197), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Phospho-Tyr869), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (phospho-Tyr1110), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Ab-1070), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Ab-1092), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Ab-678), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Ab-693), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Ab-1172), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Ab-1197), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Ab-869), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Ab-1110), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Phospho-Ser1070) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Phospho-Tyr1092) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR(Phospho-Tyr1172) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Phospho-Tyr1197) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Phospho-Tyr869) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (phospho-Tyr1110) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (External Domain), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (Internal Domain), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR pTyr 845, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR (a.a. 1165-1186), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR dpTyr 1173, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR, Activated pTyr 1173, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR pS1047, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR pThr 654, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR, pTyr 1045, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGF Receptor (non-ligand binding site), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGF Receptor (ligand binding site), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGF Receptor, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with Rabbit anti EGFR (a.a. 1168-1181), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with Rabbit anti EGF Receptor, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR Human Sf9, Protein (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR Human, Protein (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR Human Sf9, Protein (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with Anti-Epidermal Growth Factor Receptor (EGFR) pY1197, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [ICR10] (FITC), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [29.1], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR phospho Y1148, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [SP9] (ready-to-use), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [EGFR1], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGF R, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR phospho Y1173, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR phospho Y1068, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR phospho Y845, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [F4], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [ICR61], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [R19/48], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [H9B4], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [F4], IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR phospho Y1086, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR phospho Y992, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGFR [F4] (FITC), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with EGF R, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with epidermal growth factor receptor isoform a precursor, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with ASK1, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with ASK1 (Phospho-Ser83), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with ASK1 (Phospho-Ser966), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with ASK1 (Ab-83), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with ASK1 (Ab-966), IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with ASK1 (Phospho-Ser83) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with ASK1 (Phospho-Ser966) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with Rabbit anti ASK-1 pS83, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with Anti-ASK-1 phospho specific pS83, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with Anti-MARK2 pT595, IgG (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with Protein kinase C iota type, Protein (GenWay Catalog #: 10-288-22342F).

14-3-3 protein zeta/delta interacts with PKC iota + PKC lambda phospho T555 + T563, IgG (GenWay Catalog #: 10-288-22342F).

SUGGESTED PROTEIN REAGENTS - GenWay offers reagents to facilitate your research with cell-based assays, Mass Spectrometry, standards, calibrators, Western blot, cell culture, antibiotics, microwell substrates, and more!

BACKGROUND REFERENCES for YWHAZ PROTEIN:

Background references for antibody target are not specific to GenWay products

[1] Coblitz,B., Shikano,S., Wu,M., Gabelli,S.B., Cockrell,L.M., Spieker,M., Hanyu,Y., Fu,H., Amzel,L.M. and Li,M.
     C-terminal recognition by 14-3-3 proteins for surface expression of membrane receptors
[2] Obsilova,V., Vecer,J., Herman,P., Pabianova,A., Sulc,M., Teisinger,J., Boura,E. and Obsil,T.
     14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4
[3] Izaki,T., Kamakura,S., Kohjima,M. and Sumimoto,H., et al.
     Phosphorylation-dependent binding of 14-3-3 to Par3beta, a human Par3-related cell polarity protein
[4] Kino,T., De Martino,M.U., Charmandari,E., Ichijo,T., Outas,T. and Chrousos,G.P.
     HIV-1 accessory protein Vpr inhibits the effect of insulin on the Foxo subfamily of forkhead transcription factors by interfering with their binding to 14-3-3 proteins: potential clinical implications regarding the insulin resistance of HIV-1-infected patients
[5] Silhan,J., Obsilova,V., Vecer,J., Herman,P., Sulc,M., Teisinger,J. and Obsil,T.
     14-3-3 protein C-terminal stretch occupies ligand binding groove and is displaced by phosphopeptide binding
[6] , Zupan L.A., Steffens D.L., Berry C.A., Landt M.L., Gross R.W.
     Cloning and expression of a human 14-3-3 protein mediating phospholipolysis. Identification of an arachidonoyl-enzyme intermediate during catalysis.
[7] , Seluja G.A., Pietromonaco S.F., Elias L.
     Two unique 5' untranslated regions in mRNAs encoding human 14-3-3 zeta: differential expression in hemopoietic cells.
[8] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
     Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
[9] , Gevaert K., Goethals M., Martens L., Van Damme J., Staes A., Thomas G.R., Vandekerckhove J.
     Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
[10] , Bienvenut W.V., Potts A., Barblan J., Claeys D., Quadroni M.
     Unpublished observations (NOV-2005).

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: YWHAZ protein is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of YWHAZ protein vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about YWHAZ protein, all related information, articles, resources about YWHAZ protein are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

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