DLX5 protein, Homeobox protein DLX-5 recombinant protein

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Homeobox protein DLX-5 recombinant protein

Catalog Number: 10-288-22362F

Buy DLX5 protein -

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Related Product Names:

- DLX5 protein; DLX5; Homeobox protein DLX-5
- Distal-less homeobox 5

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: DLX5	Gene Name Synonym: N/A
Gi #: 4885187	NCBI Acc #: NP_005212.1	Swiss Prot Acc #: P56178
Length (aa): 289	Mol. Weight (Da): 31540	Chrom Location: 7q22

Linear Protein Map of Expressed Protein (sequence source from above GI#)

Fusion: His-Tag at N-terminus.

Source/Host: E Coli

Purity/Purification: 90%

Crossreactivity: human

Format: 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3.

Storage: -70 degree C. Avoid frequent freeze and thaw.

Stability: 6-12 months at -70 degree C.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for DLX5 PROTEIN:

MS, SDS: Tested

ELISA, Western Blot: Not Tested

TESTING: (secondary reagents and protocols )

SDS: Analysis of DLX5 Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining. ( anti-DLX5 protein )

DLX5 protein SDS image
DLX5

DLX5 PROTEIN TARGET DESCRIPTION:

Synonym Names for DLX5 protein: DLX5; Distal-less homeobox 5

Subunit: Interacts with G22P1 (Ku70).

Subcellular Location: Nucleus (Potential).

Developmental Stage: First expressed in embryos at 8.5-9 days in facial and branchial arch mesenchyme, otic vesicles and frontonasal ectoderm around olfactory placodes, a day later expression is seen in the developing forebrain in primordia of the ganglionic eminence and ventral diencephalic regions. In day 12.5 embryos, expressed in the brain and bones, and also in all skeletal structures of midgestation embryos after the first cartilage formation. Expression remains unaltered in both brain and skeleton in day 15 embryos and slowly decreases in day 17 embryos.

Similarity: Belongs to the distal-less homeobox family.

Similarity: Contains 1 homeobox DNA-binding domain.

Summary: This protein is a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.

Homeobox protein DLX-5 reacts with human.

OMIM: 600028; gene. [NCBI / EBI]

SUGGESTED PROTEIN REAGENTS - GenWay offers reagents to facilitate your research with cell-based assays, Mass Spectrometry, standards, calibrators, Western blot, cell culture, antibiotics, microwell substrates, and more!

BACKGROUND REFERENCES for DLX5 PROTEIN:

Background references for antibody target are not specific to GenWay products

[1] Morsczeck,C., et al.
     Gene expression of runx2, Osterix, c-fos, DLX-3, DLX-5, and MSX-2 in dental follicle cells during osteogenic differentiation in vitro
[2] Kimura,K., Wakamatsu,A., Suzuki,Y., Ota,T., Nishikawa,T., Yamashita,R., Yamamoto,J., Sekine,M., Tsuritani,K., Wakaguri,H.,, et al.
     Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes
[3] Bapat,S. and Galande,S., et al.
     Association by guilt: identification of DLX5 as a target for MeCP2 provides a molecular link between genomic imprinting and Rett syndrome
[4] Okita,C., Meguro,M., Hoshiya,H., Haruta,M., Sakamoto,Y.K. and Oshimura,M.
     A new imprinted cluster on the human chromosome 7q21-q31, identified by human-mouse monochromosomal hybrids
[5] Scherer,S.W., Cheung,J., MacDonald,J.R., Osborne,L.R., Nakabayashi,K., Herbrick,J.A., Carson,A.R., Parker-Katiraee,L.,, et al.
     Human chromosome 7: DNA sequence and biology
[6] , Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., et al.
     Complete sequencing and characterization of 21,243 full-length human cDNAs.
[7] , Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., et al.
     The DNA sequence of human chromosome 7.
[8] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
     Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
[9] , Simeone A., Acampora D., Pannese M., D'Esposito M., Stornaiuolo A., Gulisano M., Mallamaci A., Kastury K., Druck T., Huebner K., et al.
     Cloning and characterization of two members of the vertebrate Dlx gene family.
[10] , Willis D.M., Loewy A.P., Charlton-Kachigian N., Shao J.-S., Ornitz D.M., Towler D.A.
     Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex.

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Precautions: DLX5 protein is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of DLX5 protein vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about DLX5 protein, all related information, articles, resources about DLX5 protein are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

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