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Eukaryotic translation initiation factor 3 subunit 3 recombinant protein Printer Friendly Datasheet
Catalog Number: 10-288-22535F
Buy EIF3S3 protein - Size:   
  Related Product Names:
- EIF3S3 protein; EIF3S3; eIF3-p40; MGC102958; eIF3-gamma; Eukaryotic translation initiation factor 3 subunit 3
- eIF-3 gamma; eIF3 p40 subunit; eIF3h; Eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
 Gene Name: EIF3S3  Gene Name Synonym: eIF3-p40; MGC102958; eIF3-gamma

 Gi #: 4503515

 NCBI Acc #: NP_003747.1

 Swiss Prot Acc #: O15372

 Length (aa): 352

 Mol. Weight (Da): 39930

 Chrom Location: 8q24.11
EIF3S3
Linear Protein Map of Expressed Protein (sequence source from above GI#)
 Fusion: His-tag at N-terminus.

 Source/Host: E Coli

 Purity/Purification: 90%

 Crossreactivity: human

 Format: 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3, 10mM DTT.

 Storage: -70 degree C. Avoid frequent freeze and thaw.

 Stability: 6-12 months at -70 degree C.

 Shipping: Products may be shipped on ice pack or dry ice.
 APPLICATIONS for EIF3S3 PROTEIN:
 MS, SDS: Tested
 ELISA, Western Blot: Not Tested
 TESTING: (secondary reagents and protocols )
 SDS: Analysis of EIF3S3 Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining. ( anti-EIF3S3 protein )

EIF3S3 protein SDS image
EIF3S3

 EIF3S3 PROTEIN TARGET DESCRIPTION:
Synonym Names for EIF3S3 protein: EIF3S3; eIF3-p40; MGC102958; eIF3-gamma; eIF-3 gamma; eIF3 p40 subunit; eIF3h; Eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa

Function: Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. Associates with the p170 subunit of EIF3.

Subunit: eIF-3 is composed of at least 12 different subunits.

Similarity: Belongs to the peptidase M67 family [view classification].

Similarity: Contains 1 MPN (JAB/Mov34) domain.

Eukaryotic translation initiation factor 3 subunit 3 reacts with human.

OMIM: 603912; gene. [NCBI / EBI]

Pathways:
Reactome Event:Gene Expression 74160
Reactome Event:Translation 72766
 PRODUCT INTERACTIONS:
SUGGESTED PROTEIN REAGENTS - GenWay offers reagents to facilitate your research with cell-based assays, Mass Spectrometry, standards, calibrators, Western blot, cell culture, antibiotics, microwell substrates, and more!
 BACKGROUND REFERENCES for EIF3S3 PROTEIN:
Background references for antibody target are not specific to GenWay products
[1] Kimura,K., Wakamatsu,A., Suzuki,Y., Ota,T., Nishikawa,T., Yamashita,R., Yamamoto,J., Sekine,M., Tsuritani,K., Wakaguri,H.,, et al.
     Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes
[2] Savinainen,K.J., Linja,M.J., Saramaki,O.R., Tammela,T.L., Chang,G.T., Brinkmann,A.O. and Visakorpi,T.
     Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer
[3] Okamoto,H., Yasui,K., Zhao,C., Arii,S. and Inazawa,J., et al.
     PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas
[4] Mayeur,G.L., Fraser,C.S., Peiretti,F., Block,K.L. and Hershey,J.W., et al.
     Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3
[5] Morris,J.A., Kandpal,G., Ma,L. and Austin,C.P., et al.
     DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation
[6] , Asano K., Vornlocher H.-P., Richter-Cook N.J., Merrick W.C., Hinnebusch A.G., Hershey J.W.B.
     Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly.
[7] , Schmidt O.G., von Holtum D., Gross S., Horsthemke B., Luedecke H.-J.
     The gene encoding the p40 subunit of the translation initiation factor eIF3 has 8 exons, maps to the Langer-Giedion syndrome region on chromosome 8q24, but is not the TRPS gene.
[8] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
     Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: EIF3S3 protein is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of EIF3S3 protein vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about EIF3S3 protein, all related information, articles, resources about EIF3S3 protein are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.
 SERVICES AVAILABLE for EIF3S3 PROTEIN:
 Are you interested in ELISA development for this protein?
 ELISA kit and other assay development services.
 Protein Expression Services for EIF3S3
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 Please inquire about antigen, protein availability or custom chicken igy antibody services.

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