Alphabetical Listing of Primary Antibodies:
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0-4
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5-9
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A
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B
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C
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D
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E
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F
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G
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H
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I
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J
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K
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M
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N
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P
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R
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S
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W
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X
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Y
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Alphabetical Listing of Proteins:
f
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0-4
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5-9
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A
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B
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C
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D
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E
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F
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G
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H
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I
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J
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K
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L
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M
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N
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O
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P
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Q
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R
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S
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T
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U
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V
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W
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X
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Y
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Peptides
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Secondary Antibodies
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ELISA Kits
activating transcription factor 7 interacting protein (ATF7IP) Antibody, Mouse Monoclonal Antibody
Catalog Number: 20-372-60151
Buy ATF7IP antibody -
Size:
0.1 mg ($350.00)
Related Product Names:
- ATF7IP antibody; ATF7IP; MCAF; p621; FLJ10139; FLJ10688; activating transcription factor 7 interacting protein (ATF7IP)
- Mouse monoclonal anti-human ATF7IP antibody; ATFa-associated modulator; hAM; ATF-IP; ATF-interacting protein; MBD1-containing chromatin-associated factor 1; P621; Homo sapiens activating transcription factor 7 interacting protein (ATF7IP), mRNA; Activating transcription factor 7-interacting protein 1
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact
sales@genwaybio.com
.
Gene Name:
ATF7IP
Gene Name Synonym:
MCAF; p621; FLJ10139; FLJ10688
Gi #:
38261961
NCBI Acc #:
NM_018179.3
Swiss Prot Acc #:
Q6VMQ6
Length (aa):
N/A
Mol. Weight (Da):
136392
Chrom Location:
N/A
Clone:
2052C2a
IGG Subclass:
IgG1
Preparation:
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility:
Filtered through a 0.22 um membrane.
Source/Host:
Mouse
Clonality:
Monoclonal
Crossreactivity:
Human
Format:
Mouse monoclonal anti-human ATF7IP antibody in PBS (3.0 mM KCl, 1.5 mM K2HPO4, 140 mM NaCl, 8.0 mM Na2HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3)
Storage:
Store at 2-8 C for up to one year. We recommend storing at –20 C for long-term storage. Avoid repeat freezing and thawing cycles.
Shipping:
Products may be shipped on ice pack or dry ice.
APPLICATIONS for ATF7IP ANTIBODY:
DB: Tested
TESTING: (
secondary reagents
and
protocols
)
Western Blot ( anti-ATF7IP )
ATF7IP antibody tern B image
ATF7IP ANTIBODY TARGET DESCRIPTION:
Synonym Names for ATF7IP antibody:
ATF7IP; MCAF; p621; FLJ10139; FLJ10688; Mouse monoclonal anti-human ATF7IP antibody; ATFa-associated modulator; hAM; ATF-IP; ATF-interacting protein; MBD1-containing chromatin-associated factor 1; P621; Homo sapiens activating transcription factor 7 interacting protein (ATF7IP), mRNA; Activating transcription factor 7-interacting protein 1
Function:
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9'. The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation.
Subunit:
Interacts with MBD1; the interaction is enhanced when MBD1 is sumoylated. Probably forms a complex with SETDB1 and MBD1. Interacts with SUMO ubiquitin-like proteins (SUMO1, SUNO2 and SUMO3), with a preference for SUMO2 and SUMO3. Interacts with SP1, ATF7 and ZHX1. Interacts with Epstein-Barr virus BRLF1/Rta protein, leading to promote and regulate host genes in Epstein-Barr virus-infected cells.
Subcellular Location:
Nucleus (By similarity).
Similarity:
Belongs to the MCAF family.
Similarity:
Contains 1 fibronectin type-III domain.
activating transcription factor 7 interacting protein (ATF7IP) reacts with human.
Products similar to ATF7IP antibody:
IgG
MCP1 [S14], IgG
MCP1, IgG
MCP1 [S101], IgG
MCP1*B1G1, IgG
Human Macrophage/MCAF,, Protein
SUGGESTED ANITBODY REAGENTS
- GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
BACKGROUND REFERENCES for ATF7IP ANTIBODY:
Background references for antibody target are not specific to GenWay products
[1]
Olsen,J.V., Blagoev,B., Gnad,F., Macek,B., Kumar,C., Mortensen,P. and Mann,M.
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
[2]
Uchimura,Y., Ichimura,T., Uwada,J., Tachibana,T., Sugahara,S., Nakao,M. and Saitoh,H.
Involvement of SUMO modification in MBD1- and MCAF1-mediated heterochromatin formation
[3]
Chang,L.K., Chung,J.Y., Hong,Y.R., Ichimura,T., Nakao,M. and Liu,S.T.
Activation of Sp1-mediated transcription by Rta of Epstein-Barr virus via an interaction with MCAF1
[4]
Ichimura,T., Watanabe,S., Sakamoto,Y., Aoto,T., Fujita,N. and Nakao,M.
Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins
[5]
Colland,F., Jacq,X., Trouplin,V., Mougin,C., Groizeleau,C., Hamburger,A., Meil,A., Wojcik,J., Legrain,P. and Gauthier,J.M.
Functional proteomics mapping of a human signaling pathway
[6]
Wang H., An W., Cao R., Xia L., Erdjument-Bromage H., Chatton B., Tempst P., Roeder R.G., Zhang Y.
mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression.
[7]
Fujita N., Watanabe S., Ichimura T., Ohkuma Y., Chiba T., Saya H., Nakao M.
MCAF mediates MBD1-dependent transcriptional repression.
[8]
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., et al.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
[9]
Gunther M., Laithier M., Brison O.
A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.
[10]
Yamada K., Kawata H., Shou Z., Hirano S., Mizutani T., Yazawa T., Sekiguchi T., Yoshino M., Kajitani T., Miyamoto K., et al.
Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3.
Order Confirmation:
Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions:
ATF7IP antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes:
During shipment, small volumes of ATF7IP antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright:
This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about ATF7IP antibody, all related information, articles, resources about ATF7IP antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer:
For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.
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