DDX3X antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (DDX3X) Antibody, Mouse Monoclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (DDX3X) Antibody, Mouse Monoclonal Antibody

Catalog Number: 20-372-60209

Buy DDX3X antibody -

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Related Product Names:

- DDX3X antibody; DDX3X; DBX; DDX3; HLP2; DDX14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (DDX3X)
- Mouse monoclonal anti-human DDX3X antibody; EC 3.6.1.-; DEAD box protein 3, X-chromosomal; Helicase-like protein 2; HLP2; DEAD box, X isoform; Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (DDX3X), mRNA; ATP-dependent RNA helicase DDX3X

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: DDX3X	Gene Name Synonym: DBX; DDX3; HLP2; DDX14
Gi #: 87196350	NCBI Acc #: NM_001356.3	Swiss Prot Acc #: O00571
Length (aa): N/A	Mol. Weight (Da): 73243	Chrom Location: N/A

Clone: 2253C5a

IGG Subclass: IgG1

Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.

Sterility: Filtered through a 0.22 um membrane.

Source/Host: Mouse

Clonality: Monoclonal

Crossreactivity: Human

Format: Mouse monoclonal anti-human DDX3X antibody in PBS (3.0 mM KCl, 1.5 mM K2HPO4, 140 mM NaCl, 8.0 mM Na2HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3)

Storage: Store at 2-8 C for up to one year. We recommend storing at –20 C for long-term storage. Avoid repeat freezing and thawing cycles.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for DDX3X ANTIBODY:

DB, RIA, WB: Tested

TESTING: (secondary reagents and protocols )

Western Blot ( anti-DDX3X )

DDX3X antibody tern B image
DDX3X

Western Blot ( anti-DDX3X )

DDX3X antibody tern B image
DDX3X

Western Blot ( anti-DDX3X )

DDX3X antibody tern B image
DDX3X

Western Blot ( anti-DDX3X )

DDX3X antibody tern B image
DDX3X

DDX3X ANTIBODY TARGET DESCRIPTION:

Synonym Names for DDX3X antibody: DDX3X; DBX; DDX3; HLP2; DDX14; Mouse monoclonal anti-human DDX3X antibody; EC 3.6.1.-; DEAD box protein 3, X-chromosomal; Helicase-like protein 2; HLP2; DEAD box, X isoform; Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (DDX3X), mRNA; ATP-dependent RNA helicase DDX3X

Function: ATP-dependent RNA helicase. Acts as a cofactor for XPO1-mediated nuclear export of incompletely spliced HIV-1 Rev RNAs. Also involved in HIV-1 replication. Interacts specifically with hepatitis C virus core protein resulting in a change in intracellular location.

Subunit: Found in a complex with Rev and XPO1. Interacts with XPO1. Interacts with HCV core protein.

Subcellular Location: Nucleus speckle. Cytoplasm. Note=Located predominantly in nuclear speckles and, at low levels, throughout the cytoplasm. Located to the outer side of nuclear pore complexes (NPC). Shuttles between the nucleus and the cytoplasm in a XPO1-dependent manner.

Similarity: Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.

Similarity: Contains 1 helicase ATP-binding domain.

Similarity: Contains 1 helicase C-terminal domain.

Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This protein is a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This protein has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog.

DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (DDX3X) reacts with human.

OMIM: 300160; gene. [NCBI / EBI]

Products similar to DDX3X antibody:

IgG

DDX31 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 31), IgG

HLA-B associated transcript 1 (BAT1), transcript variant 1, mRNA, IgG

Rabbit anti DDX3, N-term., IgG

DEAH (Asp-Glu-Ala-His) box polypeptide 38 (DHX38), mRNA, IgG

DDX39 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 39), IgG

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for DDX3X ANTIBODY:

Background references for antibody target are not specific to GenWay products

[1] Franca,R., Belfiore,A., Spadari,S. and Maga,G., et al.
     Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity
[2] Chao,C.H., Chen,C.M., Cheng,P.L., Shih,J.W., Tsou,A.P. and Lee,Y.H., et al.
     DDX3, a DEAD box RNA helicase with tumor growth-suppressive property and transcriptional regulation activity of the p21waf1/cip1 promoter, is a candidate tumor suppressor
[3] Chang,P.C., Chi,C.W., Chau,G.Y., Li,F.Y., Tsai,Y.H., Wu,J.C. and Wu Lee,Y.H.
     DDX3, a DEAD box RNA helicase, is deregulated in hepatitis virus-associated hepatocellular carcinoma and is involved in cell growth control
[4] Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J., Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and, et al.
     Transcriptome analysis of human gastric cancer
[5] Gevaert,K., Staes,A., Van Damme,J., De Groot,S., Hugelier,K., Demol,H., Martens,L., Goethals,M. and Vandekerckhove,J.
     Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC
[6] Chung J., Lee S.-G., Song K.
     Identification of a human homolog of a putative RNA helicase gene (mDEAD3) expressed in mouse erythroid cells.
[7] Owsianka A.M., Patel A.H.
     Hepatitis C virus core protein interacts with a human DEAD box protein DDX3.
[8] Lahn B.T., Page D.C.
     Functional coherence of the human Y chromosome.
[9] Yaguee J., Alvarez I., Rognan D., Ramos M., Vazquez J., Lopez de Castro J.A.
     An N-acetylated natural ligand of human histocompatibility leukocyte antigen (HLA)-B39. Classical major histocompatibility complex class I proteins bind peptides with a blocked NH(2) terminus in vivo.
[10] Yedavalli V.S., Neuveut C., Chi Y.-H., Kleiman L., Jeang K.-T.
     Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: DDX3X antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of DDX3X antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about DDX3X antibody, all related information, articles, resources about DDX3X antibody are being stored on our online database. Let us know if you have questions regarding this product.

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