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LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) Antibody, Mouse Monoclonal Antibody Printer Friendly Datasheet
Catalog Number: 20-372-60255
Buy LSM8 antibody - Size:   
  Related Product Names:
- LSM8 antibody; LSM8; YJR022W; LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8)
- Mouse monoclonal anti-human LSM8 antibody; N/A; Homo sapiens LSM8 homolog, U6 small nuclear RNA associated (S cerevisiae) (LSM8), mRNA; U6 snRNA-associated Sm-like protein LSm8
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
 Gene Name: LSM8  Gene Name Synonym: YJR022W

 Gi #: 93141217

 NCBI Acc #: NM_016200.3

 Swiss Prot Acc #: O95777

 Length (aa): N/A

 Mol. Weight (Da): 10403

 Chrom Location: N/A
 Clone: 2527C6a

 IGG Subclass: IgG1

 Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.

 Sterility: Filtered through a 0.22 um membrane.

 Source/Host: Mouse

 Clonality: Monoclonal

 Crossreactivity: Human

 Format: Mouse monoclonal anti-human LSM8 antibody in PBS (3.0 mM KCl, 1.5 mM K2HPO4, 140 mM NaCl, 8.0 mM Na2HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3)

 Storage: Store at 2-8 C for up to one year. We recommend storing at –20 C for long-term storage. Avoid repeat freezing and thawing cycles.

 Shipping: Products may be shipped on ice pack or dry ice.
 APPLICATIONS for LSM8 ANTIBODY:
 DB: Tested
 TESTING: (secondary reagents and protocols )
 Western Blot ( anti-LSM8 )

LSM8 antibody tern B image
LSM8

 LSM8 ANTIBODY TARGET DESCRIPTION:
Synonym Names for LSM8 antibody: LSM8; YJR022W; Mouse monoclonal anti-human LSM8 antibody; N/A; Homo sapiens LSM8 homolog, U6 small nuclear RNA associated (S cerevisiae) (LSM8), mRNA; U6 snRNA-associated Sm-like protein LSm8

Function: Binds specifically to the 3'-terminal U-tract of U6 snRNA.

Subunit: LSm subunits form a heteromer with a donut shape.

Subcellular Location: Nucleus (Potential).

Similarity: Belongs to the snRNP Sm proteins family.

Summary: This protein is a member of the LSm family and encodes a protein with a closed barrel shape, made up of five anti-parallel beta strands and an alpha helix. The protein partners with six paralogs to form a heteroheptameric ring which transiently binds RNAs and is involved in the general maturation of RNA in the nucleus. COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-32 DB275674.1 1-32 33-133 DA318705.1 1-101 134-645 BC022440.1 4-515 646-682 DA112078.1 515-551 683-724 BC022440.1 555-596 725-1133 AL600056.1 8-416 1134-1303 BC022440.1 1006-1175 1304-1317 BM972935.1 7-20 c

LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) reacts with human.

OMIM: 607288; gene. [NCBI / EBI]
 PRODUCT INTERACTIONS:
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with DBF4 homolog (S. cerevisiae) (DBF4), mRNA, IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with DCP1A (DCP1 decapping enzyme homolog A (S. cerevisiae)), IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with EXOSC10 (exosome component 10), IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with PM/Scl 100 Human, Protein (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with TFII I, IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with TFII I, IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with TFIII, IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with TFIII, IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with IL28-R alpha, IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with LSM2 (LSM2 homolog. U6 small nuclear RNA associated (S. cerevisiae)), IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with U6 snRNA-associated Sm-like protein LSm4, Protein (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with RENT1, IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with RENT1, IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with RENT1, IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide 16kDa), IgG (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with Sm/RNP Antigen, Native_Protein (GenWay Catalog #: 20-372-60255).
 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM8) interacts with Sm/RNP Antigen, Native_Protein (GenWay Catalog #: 20-372-60255).
SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
 BACKGROUND REFERENCES for LSM8 ANTIBODY:
Background references for antibody target are not specific to GenWay products
[1] Khusial,P., Plaag,R. and Zieve,G.W., et al.
     LSm proteins form heptameric rings that bind to RNA via repeating motifs
[2] Lehner,B. and Sanderson,C.M., et al.
     A protein interaction framework for human mRNA degradation
[3] Lehner,B., Semple,J.I., Brown,S.E., Counsell,D., Campbell,R.D. and Sanderson,C.M.
     Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region
[4] Hillier,L.W., Fulton,R.S., Fulton,L.A., Graves,T.A., Pepin,K.H., Wagner-McPherson,C., Layman,D., Maas,J., Jaeger,S., Walker,R.,, et al.
     The DNA sequence of human chromosome 7
[5] Eystathioy,T., Peebles,C.L., Hamel,J.C., Vaughn,J.H. and Chan,E.K., et al.
     Autoantibody to hLSm4 and the heptameric LSm complex in anti-Sm sera
[6] Achsel T., Brahms H., Kastner B., Bachi A., Wilm M., Luehrmann R.
     A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.
[7] Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., et al.
     The DNA sequence of human chromosome 7.
[8] Bienvenut W.V.
     Unpublished observations (JUL-2005).
Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: LSM8 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of LSM8 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about LSM8 antibody, all related information, articles, resources about LSM8 antibody are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

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