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| CD151 Antibody, Mouse Monoclonal Antibody |
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| Catalog Number: 20-783-71070 |
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| Related Product Names:
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CD151 antibody; CD151; TSPAN24; CD151
- MOUSE ANTI HUMAN CD151; CD151; CD151 antigen |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: CD151 |
Gene Name Synonym: TSPAN24 |
Gi #:
49457149 |
NCBI Acc #:
CAG46895.1 |
Swiss Prot Acc #:
P48509 |
Length (aa): N/A |
Mol. Weight (Da): 28295 |
Chrom Location: N/A |
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 Specificity: CD151
NCBI Gene ID: 977
Isotype: Specificity: CD151
Clone: 11G5a
Fusion Partner: Spleen cells from immunised BALB/c mice were fused with cells of the X63.Ag8.653 mouse myeloma cell line.
Specificity Note: This product recognises the human CD151 cell surface antigen, also known as PETA-3. CD151 is expressed by epithelial cells, endothelial cells, platelets, megakaryocytes, monocytes and in the renal glomeruli and proximal and distal tubules. CD151 is not expressed by lymphocytes or granulocytes. More recently CD151 has also been shown to be expressed by erythrocytes, and to carry the MER2 blood group antigen (2).
It should be noted that CD151 is very closely associated with the alpha3 beta1 integrin in cells and co-immunoprecipitation may occur even in quite stringent conditions. (1).
Immunohistology: This product does not require protein digestion pre-treatment but results are enhanced with heat mediated antigen retrieval in 0.01M citrate buffer.
Histology: Tonsil/spleen
Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preservative Stabilisers:
Suggested Dilution: Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood
Suggested Dilution: Flow Cytometry - 1/50 - 1/100
Immunohistology - Paraffin - 1/100
Source/Host: Mouse
Clonality: Monoclonal
Crossreactivity: Human
Format: Purified
Storage: Store at +4Cor at -20Cif preferred.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Stability: 18 months from date of despatch.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for CD151 ANTIBODY: |
| IHC-F, ELISA, FACS/FC, IP, IHC-F, WB: Tested |
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| TESTING: (secondary reagents and protocols
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Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood ( anti-CD151 ) Flow Cytometry: Staining of human peripheral blood platelets with MOUSE ANTI HUMAN CD151 .
( anti-CD151 )CD151 antibody Flow Cytometry image
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| CD151 ANTIBODY TARGET DESCRIPTION: |
Synonym Names for CD151 antibody: CD151; TSPAN24; MOUSE ANTI HUMAN CD151; CD151; CD151 antigen
Function: Essential for the proper assembly of the glomerular and tubular basement membranes in kidney.
Subunit: Interacts with integrins alpha3beta1, alpha5beta1, alpha3beta1 and alpha6beta4, with CD9 and CD181.
Subcellular Location: Membrane; Multi-pass membrane protein.
Tissue Specificity: Expressed in a variety of tissues including vascular endothelium and epidermis. Expressed on erythroid cells, with a higher level of expression in erythroid precursors than on mature erythrocytes.
Induction: By HTLV-1.
Polymorphism: CD151 defines the MER2=RAPH1 antigen of the RAPH blood group system. 92% of Caucasians are MER2-positive and 8% are apparently MER2-negative.
Disease: Defects in CD151 are the cause of nephropathy with pretibial epidermolysis bullosa and deafness [MIM:609057].
Similarity: Belongs to the tetraspanin (TM4SF) family.
CD151 reacts with human.
OMIM: 179620; phenotype. [NCBI / EBI]
602243; gene. [NCBI / EBI]
609057; phenotype. [NCBI / EBI]
Products similar to CD151 antibody:
IgG
 CD151, IgG
CD151, IgG
CD151, IgG
CD151, IgG
CD151, IgG
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for CD151 ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| 1. Yauch. R.L. et al. (1998) Highly stoichiometric. stable. and specific association of integrin alpha 3 beta 1 with CD151 provides a major link to phosphatidylinositol 4-kinase. and may regulate cell migration. 2. Crew. V.K. et al. (2004) CD151. the first member of the tetraspanin (TM4) superfamily detected on erythrocytes. is essential for the correct assembly of human basement membranes in kidney and skin. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: CD151 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of CD151 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about CD151 antibody, all related information, articles, resources about CD151 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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