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| CD147 Antibody, Mouse Monoclonal Antibody |
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| Catalog Number: 20-783-71101 |
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| Related Product Names:
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BSG antibody; BSG; CD147
- MOUSE ANTI HUMAN CD147; CD147; Basigin |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: BSG |
Gene Name Synonym: N/A |
Gi #:
31076333 |
NCBI Acc #:
BAC76828.1 |
Swiss Prot Acc #:
P35613 |
Length (aa): N/A |
Mol. Weight (Da): 42200 |
Chrom Location: N/A |
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 Specificity: CD147
NCBI Gene ID: 682
Isotype: Specificity: CD147
Clone: MEM-M6/1
Specificity Note: This product recognises the human CD147 cell surface antigen, a 50-60kD glycoprotein also known as neurothelin and basigin. CD147 is broadly expressed on peripheral blood cells and by endothelial cells. Expression upon T cells is increased following activation.
Preparation: Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution: Phosphate buffered saline pH7.4
Preservative Stabilisers:
Suggested Dilution: Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood
Suggested Dilution: Flow Cytometry - 1/50 - 1/100
Western Blotting - Non-reducing conditions
Source/Host: Mouse
Clonality: Monoclonal
Crossreactivity: Human
Format: Purified
Storage: Store at +4Cor at -20Cif preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Stability: 18 months from date of despatch.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for BSG ANTIBODY: |
| FACS/FC, IP, WB: Tested |
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| TESTING: (secondary reagents and protocols
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Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood ( anti-BSG ) Flow Cytometry: Staining of red blood cells.
( anti-BSG )BSG antibody Flow Cytometry image
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| BSG ANTIBODY TARGET DESCRIPTION: |
Synonym Names for BSG antibody: BSG; MOUSE ANTI HUMAN CD147; CD147; Basigin
Function: Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes (By similarity).
Subunit: Forms homooligomers in a cis-dependent manner on the plasma membrane. Forms a complex with MMP1 at the tumor cell surface. Interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. Interacts with ATP1B2, MAG and L1CAM (By similarity). Interacts with AJAP1.
Subcellular Location: Cell membrane; Single-pass type I membrane protein (By similarity). Melanosome. Note=Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity: Present only in vascular endothelium in non-neoplastic regions of the brain whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.
Induction: Enriched on the surface of tumor cells. Up-regulated in gliomas. Its expression levels correlate with malignant potential of the tumor.
Ptm: N-glycosylated.
Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain.
CD147 reacts with human.
OMIM: 109480; gene. [NCBI / EBI]
111380; phenotype. [NCBI / EBI]
Products similar to BSG antibody:
IgG
 CD147 [MRC OX-47], IgG
EMMPRIN, IgG
CD147 [MEM-M6/1], IgG
CD147 [MEM-M6/2], IgG
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for BSG ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| 1. Koch. C. et al. (1999) T cell activation -associated epitopes of CD147 in regulation of the T cell response and their definition by antibody affinity and antigen density. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: BSG antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of BSG antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about BSG antibody, all related information, articles, resources about BSG antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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