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| CYCLIN D2 Antibody, Mouse Monoclonal Antibody |
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| Catalog Number: 20-783-71346 |
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| Related Product Names:
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CYCLIN D2 antibody; CYCLIN D2
- MOUSE ANTI CYCLIN D2; Cyclin D2; N/A |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: N/A |
Gene Name Synonym: N/A |
Gi #:
4502617 |
NCBI Acc #:
NP_001750.1 |
Swiss Prot Acc #:
P30279 |
Length (aa): N/A |
Mol. Weight (Da): N/A |
Chrom Location: N/A |
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 Specificity: CYCLIN D2
NCBI Gene ID: 894
Isotype: Specificity: CYCLIN D2
Clone: DCS-3.1
Immunogen: Full length recombinant cyclin D2 His tagged
Specificity Note: This product recognises the 34kD protein human cyclin D2. Cyclin D2 is a G1 cyclin which is required for G1 phase, progression of many normal and tumour derived cell types.
Clone DCS3.1 is reported as being suitable for use as a neutralising antibody.
Removal of sodium azide is recommended prior to use in functional assays. We recommend the use of for this purpose.
Histology: U-2-OS sarcoma cells fixed with methanol/acetone
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers:
Source/Host: Mouse
Clonality: Monoclonal
Crossreactivity: Target Species: Human
Reacts with: Rat. Mouse N.B.
Format: Purified
Storage: Store at +4Cor at -20Cif preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Stability: 18 months from date of despatch.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for CYCLIN D2 ANTIBODY: |
| IHC-F, IP, WB: Tested |
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| CYCLIN D2 ANTIBODY TARGET DESCRIPTION: |
Synonym Names for CYCLIN D2 antibody: N/A; MOUSE ANTI CYCLIN D2; Cyclin D2; N/A
Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.
Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. [provided by RefSeq].
CYCLIN D2 reacts with target species: human
reacts with: rat. mouse n.b..
OMIM: NCBI [123833]
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for CYCLIN D2 ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| 1. Lukas. J. et al. (1995) Cyclin D2 is a moderately oscillating nucleoprotein required for G1 phase progression in specific cell types. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: CYCLIN D2 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of CYCLIN D2 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about CYCLIN D2 antibody, all related information, articles, resources about CYCLIN D2 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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