S100A1 antibody, S100 Antibody, Rabbit Polyclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

S100 Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-783-76253

Buy S100A1 antibody -

Size:

Related Product Names:

- S100A1 antibody; S100A1; S100A; S100
- RABBIT ANTI S100 PROTEIN; Protein S100-A1

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: S100A1	Gene Name Synonym: S100A
Gi #: N/A	NCBI Acc #: NP_006262.1	Swiss Prot Acc #: P02638
Length (aa): N/A	Mol. Weight (Da): 10546	Chrom Location: N/A

Specificity: S100

NCBI Gene ID: 525716

Isotype: Specificity: S100

Immunogen: Bovine brain S-100

Specificity Note: This product reacts with human S-100 A and S-100 B. This protein is present in brain glial cells and in ependymal cells. This product also stains Schwann cells of the peripheral nervous system.

Among tumours of the human central and peripheral nervous systems, schwannomas, ependymomas and astrogliomas of different stages, including glioblastomas show positive reactions. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Langerhans cells in the skin.

Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.

Histology: Brain or skin

Antiserum Preparation: Purified Ig was prepared from whole serum by ammonium sulphate precipitation.

Buffer Solution: Phosphate buffered saline pH7.4

Preservative Stabilisers:

0.09%	Sodium Azide
1%	Bovine Serum Albumin

Suggested Dilution: Suggested Dilution: Immunohistology - Frozen - 1/10 - 1/40
Immunohistology - Paraffin - 1/10 - 1/40

Source/Host: Rabbit

Clonality: Polyclonal

Crossreactivity: Target Species: Bovine
Reacts with: Mouse. Human. Rat N.B.

Format: Concentrate

Storage: Store at +4 degree C or at -20 degree C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Stability: 18 months from date of despatch.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for S100A1 ANTIBODY:

IHC-F, IHC-F: Tested

TESTING: (secondary reagents and protocols )

IHC: Human melanoma. Formalin fixed. paraffin processed tissue. ( anti-S100A1 )

S100A1 antibody IHC image
S100A1

S100A1 ANTIBODY TARGET DESCRIPTION:

Synonym Names for S100A1 antibody: S100A1; S100A; RABBIT ANTI S100 PROTEIN; Protein S100-A1

Function: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.

Subunit: Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain.

Subcellular Location: Cytoplasm.

Tissue Specificity: Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.

Similarity: Belongs to the S-100 family.

Similarity: Contains 2 EF-hand domains.

S100 reacts with target species: bovine
reacts with: mouse. human. rat n.b..

OMIM: 176940; gene. [NCBI / EBI]

Products similar to S100A1 antibody:

IgG

S100, IgG

S100 [4B3], IgG

S100A10, IgG

S100 protein, IgG

S100A11, IgG

Native_Protein

Human Brain S-100 Protein, Native_Protein

S100A6, Native_Protein

S100A11: Human, Recombinant, E Coli, Protein

S100A10: Human, Recombinant, E Coli, Protein

S100A11: Human, Recombinant, E Coli, Protein

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for S100A1 ANTIBODY:

Background references for antibody target are not specific to GenWay products

1. Moore. B.W. (1965) A soluble protein characteristic of the nervous system. 2. Kindblom. L.G. et al. (1984) S-100 protein in melanocytic tumours. Acta. Path. Micro. Immunol Scand. Sect. A 92: 219-230.3. Kindblom. L.G. et al. (1984) S-100 protein in melanocytic tumors. An immunohistochemical investigation of benign and malignant melanocytic tumors and metastases of malignant melanoma and a characterization of the antigen in comparison to human brain. 4. Lauriola. L. et al. (1984) Detection of S-100 labelled cells in nasopharyngeal carcinoma.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: S100A1 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of S100A1 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about S100A1 antibody, all related information, articles, resources about S100A1 antibody are being stored on our online database. Let us know if you have questions regarding this product.

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