Alphabetical Listing of Primary Antibodies:
f
|
0-4
|
5-9
|
A
|
B
|
C
|
D
|
E
|
F
|
G
|
H
|
I
|
J
|
K
|
L
|
M
|
N
|
O
|
P
|
Q
|
R
|
S
|
T
|
U
|
V
|
W
|
X
|
Y
|
Z
|
Alphabetical Listing of Proteins:
f
|
0-4
|
5-9
|
A
|
B
|
C
|
D
|
E
|
F
|
G
|
H
|
I
|
J
|
K
|
L
|
M
|
N
|
O
|
P
|
Q
|
R
|
S
|
T
|
U
|
V
|
W
|
X
|
Y
|
Z
|
Peptides
|
Secondary Antibodies
|
ELISA Kits
CYTOCHROME P450 3A4 Antibody, Rabbit Polyclonal Antibody
Catalog Number: 18-783-76478
Buy CYTOCHROME P450 3A4 antibody -
Size:
0.05 ml ($530.00)
Related Product Names:
- CYTOCHROME P450 3A4 antibody; CYTOCHROME P450 3A4
- RABBIT ANTI HUMAN CYTOCHROME P450 3A4; Cytochrome P450, subfamily IIIA, polypeptide 4; N/A
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact
sales@genwaybio.com
.
Gene Name:
N/A
Gene Name Synonym:
N/A
Gi #:
13435386
NCBI Acc #:
NP_059488.2
Swiss Prot Acc #:
P08684
Length (aa):
N/A
Mol. Weight (Da):
N/A
Chrom Location:
N/A
Specificity:
CYTOCHROME P450 3A4
NCBI Gene ID:
1576
Isotype:
Polyclonal IgG
Product Form:
Serum - liquid
Immunogen:
Purified human CYP3A4 expressed in
E.Coli
Specificity Note:
This product recognises human cytochrome p450 3A4 (CYP3A4). P450 enzymes are divided into two groups: steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members:CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1.
Antiserum Preparation:
Antisera to human CYP3A4 were raised by repeated immunisation of rabbits with highly purified antigen.
Preservative Stabilisers:
0.09% Sodium Azide
Suggested Dilution:
Suggested Dilution: Western Blotting - 1:5000 - 1:10000
Source/Host:
Rabbit
Clonality:
Polyclonal
Crossreactivity:
Human
Format:
Serum
Storage:
Store at +4 degree C or at -20 degree C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Stability:
18 months from date of despatch.
Shipping:
Products may be shipped on ice pack or dry ice.
APPLICATIONS for CYTOCHROME P450 3A4 ANTIBODY:
WB: Tested
TESTING: (
secondary reagents
and
protocols
)
Not Available
CYTOCHROME P450 3A4 ANTIBODY TARGET DESCRIPTION:
Synonym Names for CYTOCHROME P450 3A4 antibody:
N/A; RABBIT ANTI HUMAN CYTOCHROME P450 3A4; Cytochrome P450, subfamily IIIA, polypeptide 4; N/A
Summary:
This protein, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This protein is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4.
Summary:
This protein, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This protein is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. [provided by RefSeq].
CYTOCHROME P450 3A4 reacts with human.
OMIM:
NCBI [
124010
]
SUGGESTED ANITBODY REAGENTS
- GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
BACKGROUND REFERENCES for CYTOCHROME P450 3A4 ANTIBODY:
Background references for antibody target are not specific to GenWay products
1. Werck-Reichhart. D. and Feyereisen. R. (2000) Protein family review Cytochromes P450: a success story. 2. Ng. P.
et al
. (2003) Production of inhibitory polyclonal antibodies against cytochrome P450s.
Order Confirmation:
Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions:
CYTOCHROME P450 3A4 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes:
During shipment, small volumes of CYTOCHROME P450 3A4 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright:
This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about CYTOCHROME P450 3A4 antibody, all related information, articles, resources about CYTOCHROME P450 3A4 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer:
For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.
GenWay is a Protein and Antibody Solutions Provider. Customer Satisfaction is Our Top Priority.
Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays.
Exact |
Advanced Search
Specific Categories
Antibodies
Secondary Antibodies
Proteins
Custom Antibody
ELISA Kits
Reagents
Products by Pathway
Protein Expression
Cell Line Development
GenWay Biotech, Inc. 6777 Nancy Ridge Drive, San Diego, CA 92121
Tel:
(858)458-0866
Fax:
(858)458-0833
Email:
sales@genwaybio.com
www.genwaybio.com
©1998 - 2010 GenWay Biotech, Inc. - All Rights Reserved
