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| 14-3-3 BETA Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-783-78339 |
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| Related Product Names:
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14-3-3 BETA antibody; 14-3-3 BETA
- RABBIT ANTI 14-3-3 BETA; Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); N/A |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: N/A |
Gene Name Synonym: N/A |
Gi #:
4559408 |
NCBI Acc #:
NP_000386.1 |
Swiss Prot Acc #:
N/A |
Length (aa): N/A |
Mol. Weight (Da): N/A |
Chrom Location: N/A |
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 Specificity: 14-3-3 BETA
Isotype: Specificity: 14-3-3 BETA
Immunogen: Synthetic peptide corresponding to acetylated N-terminal sequence of sheep 14-3-3 beta.Peptide sequence: Ac.TMDKSELVC
Specificity Note: This product recognises the acetylated N-terminal of 14-3-3 beta. It is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for it's different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein.
14-3-3 beta plays a role in the pathogenesis of systemic lupus erythematosus and is involved in negative regulation of p90 ribosomal S6 kinase activity and tuberous sclerosis tumour suppressor proteins. It also binds IGF-1 receptor, RAF1 and CDC25 phosphatases.
This product may not react with recombinant proteins that are not N-acetylated.
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
Histology: Normal brain tissue
Antiserum Preparation: Antisera to sheep 14-3-3 beta were raised by repeated immunisations of rabbit with highly purified antigen.
Preservative Stabilisers:
Suggested Dilution: Western Blot: This product detects a band of approximately 30kDa in HEK293 cell lysates.
Source/Host: Rabbit
Clonality: Polyclonal
Crossreactivity: Target Species: Sheep
Reacts with: Mouse. Rabbit. Human. Rat. Bovine N.B.
Format: Serum
Storage: Store at +4 degree C or at -20 degree C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Stability: 18 months from the date of despatch.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for 14-3-3 BETA ANTIBODY: |
| ELISA, IHC-F, WB: Tested |
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| TESTING: (secondary reagents and protocols
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| Western Blot: Detects a band/s of approximately 30kDa in HEK293 cell lysates. ( anti-14-3-3 BETA )
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| 14-3-3 BETA ANTIBODY TARGET DESCRIPTION: |
Synonym Names for 14-3-3 BETA antibody: N/A; RABBIT ANTI 14-3-3 BETA; Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); N/A
Summary: CSF2RB is a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defective CSF2RB has been reported to be associated with protein alveolar proteinosis.
Summary: The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq].
14-3-3 BETA reacts with target species: sheep
reacts with: mouse. rabbit. human. rat. bovine n.b..
OMIM: NCBI [138981]
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for 14-3-3 BETA ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| 1. Martin. H. et al. (1993) Antibodies against major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein. FEBS 331: 296-303.2. Aitken. A. et al. (2006) 14-3-3 proteins: A historic overview. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: 14-3-3 BETA antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of 14-3-3 BETA antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about 14-3-3 BETA antibody, all related information, articles, resources about 14-3-3 BETA antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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