CD3 (FITC) CD16 (RPE) Antibody (GWB-Q01588)

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Additional Information

Name CD3 (FITC) CD16 (RPE) Antibody (GWB-Q01588)
Related Product Names MOUSE ANTI HUMAN CD3:FITC/CD16:RPE Antibody, Cocktail, MOUSE ANTI HUMAN CD3:FITC/CD16:RPE
Gene Symbol CD3D
Gene Family CD
Gene id 915
Alias Symbols T3D, CD3-DELTA, CD3D
Swissprot ID P04234
Protein Name T-cell surface glycoprotein CD3 delta chain
Description of Target MOUSE ANTI HUMAN CD3:FITC/CD16:RPE
Protein Accession Num NP_000723.1
Clone S4.1/3G8
Application Info Flow Cytometry: Neat
Isotype Cocktail
Homology Human
Product Format Dual Colour combination consisting of FITC conjugated and RPE conjugated monoclonal antibodies mixed in optimal ratio - lyophilised
Specificity CD3 is a complex cell-surface glycoprotein expressed by all mature T lymphocytes. This complex comprises five different polypeptide chains, with molecular weights of 16-28kD. CD16 is a 50-65kD glycoprotein expressed by NK cells, some T cells and granulocytes. It exists in two forms, a transmembrane protein expressed on NK cells and a GPI-linked form expressed on granulocytes. CD16 functions as a low affinity receptor for IgG, and is also known as FcRIII.
This product has been developed to allow the simultaneous enumeration of Tcells and NK cells, as well as the subset of CD3+ve, CD16+ve lymphocytes
Application F
Clonality Cocktail
Format Solution: Phosphate buffered saline, Stabalizer: 0.09%, Sodium Azide. 1.0%, Bovine Serum Albumin. 5%, Sucrose, Form: Dual Colour combination consisting of FITC conjugated and RPE conjugated monoclonal antibodies mixed in optimal ratio - lyophilised
Stability 6 months from date of despatch.
Reconstitution and Storage Reconstitution: Reconstitute with 0.5ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Genway Biotech recommend that the vial is gently mixed after reconstitution.
Reactivity Human
Datasheets/Manuals Printable datasheet for GWB-Q01588
Storage Store at +4C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Species Reactivity Human
Lead Time Domestic: within 2-3 weeks delivery | International: 2-3 weeks
Intended Use Research Use Only
Key Reference 1. Beverley, P.C.L. and Callard, R.E. (1981) Distinctive functional characteristics of human T lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody. Eur. J. Immunol. 11: 329-334.
2. Edburg, J.C. et al. (1989) Human Fc gamma RIII (CD16). Isoforms with distinct allelic expression, extracellular domains, and membrane linkages on polymorphonuclear and natural killer cells. J. Immunol. 143: 1642-1649.
3. Clevers, H. et al. (1988) The transmembrane orientation of the epsilon chain of the TcR/CD3 complex. Eur. J. Immunol. 18: 705-710.
Additional Information Buffer solution: Phosphate buffered saline pH7.2
:: Preservative: 0.09% - Sodium Azide
1.0% - Bovine Serum Albumin