Mouse Anti-Human GFAP Antibody (GWB-1ZEVS4)


500 ug
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Name Mouse Anti-Human GFAP Antibody (GWB-1ZEVS4)
Availability In Stock
Gene Symbol GFAP
Gene Fullname Glial fibrillary acidic protein
Gene id 2670
Alias Symbols Glial fibrillary acidic protein, intermediate filament protein
Swissprot ID P14136
Protein Name Glial fibrillary acidic protein
Description of Target Glial fibrillary acid protein (GFAP) is a member of the type III intermediate filament family of proteins. GFAP is heavily expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and functions of the cell€™s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cell; however, its precise function remains poorly understood. In adults, GFAP levels increase in response to the proliferation of astrocytes associated with Alzheimer€™s disease, epilepsy, and multiple sclerosis. Antibodies specific for GFAP are useful as markers of astrocytic cells and neural stem cells as well as for distinguishing neoplasms of astrocytic origin from other neoplasms in the central nervous system.
Protein Accession Num NP_001124491.1; NP_001229305.1; NP_002046.1
Nucleotide Accession Num NM_001131019.2; NM_001242376.1; NM
Clone SB16a
Host Mouse
Isotype IgG1
Immunogen Recombinant human GFAP
Product Format Liquid. Borate buffered saline (pH8.2). No preservatives or amine containing buffer salts added.
Purification Purified (UNLB) antibody.
Specificity Human GFAP
Concentration 0.5 mg/ml
Application ELISA, ICC
Clonality Monoclonal
Reconstitution and Storage Store at 2-8C. Reagent is stable for the period shown on the label if stored as directed.
Datasheets/Manuals Printable datasheet for GWB-1ZEVS4
Species Reactivity Human