Thyroid Stimulating Hormone Receptor Antibody

GWB-103E07

20 µg
$195.00
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Description

Short Description: MOUSE ANTI HUMAN THYROID STIMULATING HORMONE RECEPTOR

Additional Information

Name Thyroid Stimulating Hormone Receptor Antibody
Related Product Names MOUSE ANTI HUMAN TSH RECEPTOR LGR3TSH RECEPTORTSHR
Gene Symbol TSHR
Gene Family GTSHR
Gene id 7253
Alias Symbols LGR3, CHNG1, hTSHR-I, MGC75129, TSHR
Swissprot ID P16473
Protein Name Thyrotropin receptor
Description of Target MOUSE ANTI HUMAN TSH RECEPTOR
Protein Accession Num NP_000360.2
Clone 4C1
Host Mouse
Isotype IgG2a
Replacement This antibody may replace item sc-13936 from Santa Cruz Biotechnology.
Immunogen The immunogen for anti-TSHR antibody: external domain of human TSH receptor.
Homology Human
NCBI Acc Number NP_000360.2
Product Format Purified IgG - liquid
Specificity TSH RECEPTOR
Concentration 1mg/ml
Applications C, F, P
Application Data Application #1: Staining of paraffin embedded human thyroid with Mouse anti Human TSH receptor
Application Info Flow Cytometry:    1/100 - 1/1000
Immunohistology - Paraffin:    1/1000 - 1/2000
Clonality Monoclonal
Format Solution: Phosphate buffered saline, Stabalizer: 0.09%, Sodium Azide, Form: Purified IgG - liquid
Stability 18 months from date of despatch.
Reconstitution and Storage Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Reactivity Human
Storage Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate
Datasheets/Manuals Printable datasheet for GWB-103E07
Intended Use Research Use Only
Key Reference 1. Suh, J. et al. (2003) Regulation of the phosphatidylinositol 3-Kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland. J. Biol. Chem. 278:21960-21971.
Additional Information Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the NS1/Ag4.1 myeloma cell line.
Histology Positive Control Tissue: Thyroid gland
:: Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preservative Stabilisers: 0.09% - Sodium Azide
:: Approx Protein Conc: IgG concentration 1.0 mg/ml
Buffer Solutions: Phosphate buffered saline pH7.4