Description
P-selectin, also called GMP-140, CD62, or selectin P, is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is stored in secretory granules and expressed at the plasma membrane after cell activation. It is known to play an important role in atherosclerosis. The major ligand for P-selectin on leukocytes is P-selectin glycoprotein ligand-1(PSGL-1). The standard product used in this kit is recombinant mouse P-Selectin, excluding intercellular P-Selectin and transmembrane domain. It has 42-709 amino acids sequence with the molecular mass of 99.1KDa. As a result of glycosylation, the molecular mass of 190-200KDa is revealed by SDS-PAGE.
Additional Information
| Name | Mouse P-Selectin ELISA Kit (GWB-ZZD061) |
|---|---|
| Related Product Names | Antigen CD62| CD62| CD62 antigen like family member P| CD62 antigen-like family member P| CD62P| FLJ45155| GMP 140| GMP-140| GMP140| Granule membrane protein 140| Granule membrane protein 140kDa| Granulocyte membrane protein| GRMP| LECAM3| Leukocyte end |
| Short Description | Sandwich ELISA kit of Quantitative Detection for Mouse P-Selectin |
| Sample Type | This kit is used for quantitative detection of mouse P-Selectin in cell culture supernates, serum and plasma(citrate). |
| Swissprot ID | Q01102 |
| Immunogen | NSO, W42-A709 |
| Standard Range | 62.5pg/ml-4000pg/ml. Test has a sensitivity of < 5 pg/ml |
| Specimen/Volumes | Refer to Manual |
| Concentration | Lot Specific |
| Application | ELISA |
| GI Number | 20344 |
| Stability | Four months at 4C and eight months at -20C. |
| Reactivity | Reactive to Mouse. There is no detectable cross-reactivity with other relevant proteins. |
| Kit Size | 1x96 well plate |
| Datasheets/Manuals | Printable datasheet for GWB-ZZD061 |
| Storage | Store at 4C for 6 months, at -20C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Intended Use | Research Use Only |