HIV-1 env Ag conj. to gp36 (GWB-149775)

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GWB-149775

11-511-248215

1 mg
$1,220.00

Description

Similarity: Belongs to the lentiviruses env family.

Buffer: 100mM Sodium Phosphate, pH 6.0 containing 0.05% SDS

Inactivation: Not applicable

Function: The gp120-gp41 heterodimer allows rapid transcytosis of the virus through CD4 negative cells such as simple epithelial monolayers of the intestinal, rectal and endocervical epithelial barriers. Both gp120 and gp41 specifically recognize glycosphingolipids galactosyl-ceramide (GalCer) or 3' sulfo-galactosyl-ceramide (GalS) present in the lipid rafts structures of epithelial cells. Binding to these alternative receptors allows the rapid transcytosis of the virus through the epithelial cells. This transcytotic vesicle-mediated transport of virions from the apical side to the basolateral side of the epithelial cells does not involve infection of the cells themselves.

Additional Information

Name HIV-1 env Ag conj. to gp36 (GWB-149775)
Availability Discontinued
Related Product Names HIV-1 env Ag conj. to gp36; Env polyprotein HIV-1 env Ag conj. to gp36env
Alias Symbols Recombinant Human Immunodeficiency Virus Type 1 (HIV-1), envelope antigen conjugated to gp36 HIV-2 derived peptide
Swissprot ID P03377
Protein Name Envelope glycoprotein gp160
Host E. coli/Synthetic
Product Format Purified, Liquid
Specificity HIV-1 Envelope Ag conj. to HIV-2 gp36 Peptide
Purity >95% pure (HPLC-C4, and 10% PAGE).
S-Sepharose, Ceramic Hydroxyapatite, S-300, G-25 and Dialysis.
Application ELISA, WB
Application Data Inactivation: Not applicable
Format Purified, Liquid
Reconstitution and Storage Short-term (up to 1 month) store at 2 to 8C. Long term store at -20C.
Storage Short-term (up to 1 month) store at 2-8 C. Long term store at -20 C.
Datasheets/Manuals Printable datasheet for GWB-149775
Intended Use Research Use Only
:: Buffer: 100mM Sodium Phosphate, pH 6.0 containing 0.05% SDS
Preservative: No