Human MMP13 ELISA Kit

GWB-ZZD182

1x96 well plate
$564.30
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Description

Collagenase 3 is an enzyme that in humans is encoded by the MMP13 gene. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. The expression of MMP13 in osteoarthritic cartilage and its activity against type II collagen indicates that the enzyme plays a significant role in cartilage collagen degradation and must, therefore, form part of a complex target for proposed therapeutic interventions based on collagenase inhibition. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Additional Information

Name Human MMP13 ELISA Kit
Related Product Names CLG 3| CLG3| Collagenase 3| Collagenase3| MANDP1| Matrix metalloproteinase 13| Matrix metalloproteinase-13| MMP 13| MMP-13| Mmp13| MMP13_HUMAN| UMRCASE
Short Description Sandwich ELISA kit of Quantitative Detection for Human MMP13
Sample Type This kit is used for quantitative detection of human MMP13 in cell culture supernates, serum and plasma(heparin).
Immunogen NSO, L20-C471
Standard Range 78pg/ml-5000pg/ml. Test has a sensitivity of < 5 pg/ml
Datasheets / Downloads GWB-ZZD182 Datasheet
Specimen/Volumes Refer to Manual
Swiss Prot Number A8K846
Concentration Lot Specific
Applications ELISA
GI Number 4322
Stability Four months at 4C and eight months at -20C.
Reactivity Reactive to Human. There is no detectable cross-reactivity with other relevant proteins.
Kit Size 1x96 well plate
Storage Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Intended Use Research Use Only