MMP-7 Human

GWB-70A582

10-663-45297

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Description

Similarity: Belongs to the peptidase M10A family [view classification].

Function: Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.

Additional Information

Name MMP-7 Human
Related Product Names Matrilysin, EC 3.4.24.23, Pump-1 protease, Uterine metalloproteinase, Matrix metalloproteinase-7, MMP-7, Matrin, MPSL1, PUMP-1.; EC 3.4.24.23; Pump-1 protease; Uterine metalloproteinase; Matrix metalloproteinase-7; MMP-7; Matrin MPSL1; PUMP1MMP-7 HumanMMP
Gene Symbol MMP 7
Gene id 4316
Alias Symbols Matrilysin, EC 3.4.24.23, Pump-1 protease, Uterine metalloproteinase, Matrix metalloproteinase-7, MMP-7, Matrin, MPSL1, PUMP-1, MMP7, MMP 7 Human, Matrix Metalloproteinase-7 Human Recombinant
Swissprot ID P09237
Protein Name Matrilysin
Description of Target Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3.4.24.23) cleaves a number of substrates including collagen types IV and X, elastin, fibronectin, gelatin, laminin and proteoglycans. MMP-7 is closely related to the stromelysin fam
Protein Accession Num NP_002414.1
NCBI Acc Number NP_002414.1
Product Format The protein contains the following additives 10mM HEPES (pH 7.4), 5mM CaCl2 and 150mM NaCl. Physical appearance: Sterile clear liquid solution.
Purification The MMP-7 is purified by proprietary chromatographic techniques.
Biological Activity The specific activity was found to be 6,900 U/mg. Unit Definition: One unit is defined as the digestion of 1 ug Azocoll/min at 37C.
Purity Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Source E. coli
Application Info Recommended Dilution - Western Blotting (1:1K-5K for neat serum and 1-10 ug/ml for affinity pure antibody using ECL technique).
ELISA: Control peptide can be used to coat ELISA plates at 1 ug/ml and detected with antibodies (1:10-50K for neat serum and 0.5-1 ug/ml for affinity pure). Histochemistry & Immunofluorescence: Not tested.
Format The protein (0.83 mg/ml) contains the following additives 10mM HEPES (pH 7.4), 5mM CaCl2 and 150mM NaCl.
Stability Matrilysin although stable at 4 C for 3 weeks, should be stored desiccated below -18 C.
Please prevent freeze-thaw cycles.
Reconstitution and Storage Matrilysin although stable at 4C for 3 weeks, should be stored desiccated below -18C. Please prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for GWB-70A582
Intended Use Research Use Only