1x96 well plate
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Brain-derived neurotrophic factor(BDNF) is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. It is a secreted protein with the molecular weight of 27.8kDa, consisting of 247 amino acids. It is known to promote neuronal survival and differentiation. BDNF shares substantial amino acid sequence identity with nerve growth factor(NGF). BDNF and neurotrophin-3(NT-3) are two recently cloned neurotrophic factors that are homologous to NGF. mRNA products of the BDNF and NT-3 genes are detected in the adult human brain, suggesting that these proteins are involved in the maintenance of the adult nervous system. BDNF and other neurotrophins are critically involved in long-term potentiation(LTP). BDNF-mediated LTP is induced postsynaptically. BDNF has trophic effects on serotonergic(5-HT) neurons in the central nervous system. BDNF has an essential maintenance function in the regulation of anxiety-related behavior and in food intake through central mediators in both the basal and fasted state. It plays a role in treating breathing disorders such as respiratory insufficiency after spinal injury.

Additional Information

Related Product Names Abrineurin|ANON2|Brain derived neurotrophic factor|BULN2|MGC34632|Neurotrophin
Short Description Sandwich ELISA kit of Quantitative Detection for Rat BDNF
Immunogen sf21, H129-R247
Standard Range 31.2pg/ml-2000pg/ml. Test has a sensitivity of < 2 pg/ml
Sample Type This kit is used for quantitative detection of rat BDNF in cell culture supernates, serum and plasma(heparin, EDTA, citrate).
Kit Size 1x96 well plate
Specimen/Volumes Refer to Manual
Intended Use Research Use Only
GI Number 24225
Stability Four months at 4C and eight months at -20C.
Storage Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Swiss Prot Number P23363
Concentration Lot Specific
Applications ELISA