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1x96 well plate
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Glial cell line-derived neurotrophic factor(GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily. GDNF, is a potent neurotrophic factor that promotes the survival of dopaminergic neurones in cultures including embryonic neuronal cultures. GDNF, in addition to its potential role in the differentiation and survival of central nervous system neurons, has profound effects on kidney organogenesis and the development of the peripheral nervous system.3 GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons. GDNF lies on the short arm of human chromosome 5, at 5p13.1-p13.3 ability to promote dopamine uptake in midbrain cultures. The standard product used in this kit is recombinant rat GDNF, which is a dimmer composed of two chains with 134 amino acids.

Additional Information

Name Rat GDNF ELISA Kit (GWB-ZZD114)
Related Product Names Astrocyte derived trophic factor| ATF| ATF1| ATF2| Glial cell line derived neurotrophic factor| HFB1 GDNF| hGDNF| HSCR3
Short Description Sandwich ELISA kit of Quantitative Detection for Rat GDNF
Immunogen sf21, S78-I211
Sample Type This kit is used for quantitative detection of rat GDNF in cell culture supernates, serum and plasma(heparin, EDTA).
Swissprot ID A7UGJ1
Standard Range 31.2pg/ml-2000pg/ml. Test has a sensitivity of < 4 pg/ml
Specimen/Volumes Refer to Manual
Concentration Lot Specific
Application ELISA
GI Number 25453
Stability Four months at 4C and eight months at -20C.
Reactivity Reactive to Rat. There is no detectable cross-reactivity with other relevant proteins.
Kit Size 1x96 well plate
Storage Store at 4C for 6 months, at -20C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Datasheets/Manuals Printable datasheet for GWB-ZZD114
Intended Use Research Use Only