RABBIT ANTI HUMAN MMP-16 (PRODOMAIN) Antibody

GWB-1377E8

18-783-313675

0.1 mg
$426.00

Description

Function: Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells. Ref.9

Additional Information

Name RABBIT ANTI HUMAN MMP-16 (PRODOMAIN) Antibody
Availability Discontinued
Related Product Names MT3-MMP MMPX2RABBIT ANTI HUMAN MMP-16 (PRODOMAIN)MMP16
Gene Symbol MMP16
Gene id 4325
Alias Symbols MMP-X2, C8orf57, MT-MMP2, MT-MMP3, MT3-MMP, DKFZp761D112, MMP16
Swissprot ID P51512
Protein Name Matrix metalloproteinase-16
Description of Target RABBIT ANTI HUMAN MMP-16 (PRODOMAIN)
Protein Accession Num NP_005932.2
Host Rabbit
Isotype Polyclonal IgG
Immunogen The immunogen for anti-MMP16 antibody: synthetic peptide derived from pro-domain of human MMP16 (MT3-MMP)
Homology Human
Product Format Purified IgG - liquid
Specificity MMP-16
Application C, WB
Application Info Immunohistology - Frozen:    1/25 - 1/50
Western Blotting:    1/250 - 1/500
Clonality Polyclonal Antibody
Format Purified IgG - liquid
Stability 18 months from date of despatch.
Reconstitution and Storage Store at +4oC or at -20oC if preferred.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Reactivity Human
Storage Store at +4oC or at -20oC if preferred.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation bef
Datasheets/Manuals Printable datasheet for GWB-1377E8
Species Reactivity Human
Intended Use Research Use Only
:: Preservative Stabilisers: 0.05% - Sodium Azide
Antiserum Preparation: Antisera to human MMP16 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography on Protein A.
:: Approx Protein Conc: IgG concentration 0.5mg/ml
Buffer Solutions: Phosphate buffered saline pH7.2