RECOMBINANT HUMAN TNF ALPHA (GWB-10B349)

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GWB-10B349

10-783-79199

0.01 mg
$273.00

Description

Summary: This protein is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq].

Additional Information

Name RECOMBINANT HUMAN TNF ALPHA (GWB-10B349)
Availability Discontinued
Related Product Names RECOMBINANT HUMAN TNF ALPHA
Description of Target RECOMBINANT HUMAN TNF ALPHA
Gene Symbol TNF
Gene Family TNFSF
Gene id 7124
Alias Symbols DIF, TNFA, TNFSF2, TNF-alpha, TNF
Swissprot ID P01375
Protein Name Tumor necrosis factor
Protein Accession Num NP_000585.2
Homology Human
NCBI Acc Number NP_000585.2
Product Format Purified recombinant protein - lyophilised
Molecular Weight 17.5 kD (157 amino acids)
Purity SDS PAGE: >97%
Application ELISA
GI Number 25952111
Format Purified recombinant protein - lyophilised
Reconstitution and Storage Reconstitution: Reconstitute in sterile DI water to 0.1 mg/ml for storage and further dilution.
Storage: Prior to reconstitution store at +4oC.
After reconstitution store at -20oC.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein.
Reactivity Human
Sequence Length 233
Storage Store with a desiccant at -20C.
Datasheets/Manuals Printable datasheet for GWB-10B349
Species Reactivity Human
Intended Use Research Use Only
Additional Information Activity: Approximately 2x10(e)7 units/mg. This was determined by cytolysis of murine cells in the presence of actinomycin-D.
:: Endotoxin Level: < 0.1 ng/ ug
:: Label Protein Molar Ratio: Expressed in E. coli
Preservative: None present