SYNTHETIC TETANUS TOXIN PEPTIDE (C-TERMINAL) Protein (GWB-118D68)

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GWB-118D68

10-783-79638

50 ug
$169.00
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Description

Description: This product is a 15 amino acid peptide corresponding to amino acid residues 1300 - 1314 located at the C-terminus of the Clostridium tetani tetanus toxin heavy chain according to entres protein accession number CAA28033.

Similarity: Belongs to the peptidase M27 family [view classification]. 1. Eisel. U.

Function: Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.

Additional Information

Name SYNTHETIC TETANUS TOXIN PEPTIDE (C-TERMINAL) Protein (GWB-118D68)
Related Product Names SYNTHETIC TETANUS TOXIN PEPTIDE (C-TERMINAL) TETANUS TOXINtetX
Description of Target SYNTHETIC TETANUS TOXIN PEPTIDE (C-TERMINAL)
Gene Symbol tetX
Gene id 1061100
Swissprot ID P04958
Protein Name Tetanus toxin
Protein Accession Num NP_783831.1
Peptide Sequence CDWYFVPTDEGWTND
Product Format Purified synthetic peptide - liquid
Application ELISA
Format Purified synthetic peptide - liquid
Stability 6 months from date of reconstitution.
Reconstitution and Storage Store at -20C only.
Storage in frost-free freezers is not recommended.
Following reconstitution this product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage Store at -20 degree C only.
Storage in frost-free freezers is not recommended.
Following reconstitution this product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a prec
Datasheets/Manuals Printable datasheet for GWB-118D68
Lead Time Domestic: within 2-3 weeks delivery | International: 2-3 weeks
Intended Use Research Use Only
Key Reference 1. Eisel, U. et al. (1986) Tetanus toxin: primary structure, expression in E. coli, and homology with
botulinum toxins. EMBO J. 5: 2495-2502.
Additional Information Approx Protein Conc: 1 mg/ml
:: Label Protein Molar Ratio: Solid phase synthesis
Preservative: None present