| Product Number |
GWB-10B349 |
| Product Page |
www.genwaybio.com/recombinant-human-tnf-alpha |
| Name |
RECOMBINANT HUMAN TNF ALPHA (GWB-10B349) |
| Reactivity |
Human |
| Size |
#N/A |
| Related Product Names (Synonyms) |
RECOMBINANT HUMAN TNF ALPHA |
| Molecular Weight |
17.5 kD (157 amino acids)
|
| Sequence Length |
233 |
| GI Number |
25952111 |
| NCBI Acc Number |
NP_000585.2 |
| Format |
Purified recombinant protein - lyophilised |
| Purity |
SDS PAGE: >97%
|
| Storage |
Store with a desiccant at -20C. |
| Intended Use |
Research Use Only |
| Alias Symbols |
DIF, TNFA, TNFSF2, TNF-alpha, TNF |
| Gene Family |
TNFSF |
| NCBI Gene Id |
7124 |
| Gene Symbol |
TNF |
| Product Format |
Purified recombinant protein - lyophilised |
| Description |
Summary: This protein is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq]. |
| Additional Information |
Activity: Approximately 2x10(e)7 units/mg. This was determined by cytolysis of murine cells in the presence of actinomycin-D. |
| Additional Information |
Endotoxin Level: < 0.1 ng/ ug |
| Additional Information |
Label Protein Molar Ratio: Expressed in E. coli
Preservative: None present |
| Lead Time |
Domestic: within 2-3 weeks delivery | International: 2-3 weeks |
| Protein Accession # |
NP_000585.2 |
| Protein Name |
Tumor necrosis factor |
| Reconstitution and Storage |
Reconstitution: Reconstitute in sterile DI water to 0.1 mg/ml for storage and further dilution.
Storage: Prior to reconstitution store at +4oC.
After reconstitution store at -20oC.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein.
|
| Swissprot Id |
P01375 |
| Datasheets/Manuals |
Printable datasheet for GWB-10B349 |
| Notice |
This exact product is available to purchase through Aviva Systems Biology.
Please see item number OPSA10758 to view product details and for ordering information. |
| Description of Target |
RECOMBINANT HUMAN TNF ALPHA
|
| Species Reactivity |
Human |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Application |
ELISA |
|
