Product Datasheet: GWB-18A216 - SYNTHETIC Human KALLIDIN II Protein (GWB-18A216) - Genway Biotech
 
SYNTHETIC Human KALLIDIN II Protein (GWB-18A216)
Data Sheet
 
Product Number GWB-18A216
Product Page www.genwaybio.com/synthetic-human-kallidin-ii-protein-gwb-18a216
Name SYNTHETIC Human KALLIDIN II Protein (GWB-18A216)
Reactivity Human
Size #N/A
Related Product Names (Synonyms) SYNTHETIC HUMAN KALLIDIN II BDK; KNGKALLIDIN IIKNG1
Molecular Weight 1188.2 Da_x000D_
Stability 18 months from date of despatch.
Format Purified
Purity HPLC: >99%_x000D_
Storage Prior to reconstitution store at +4 degree C.
After reconstitution store at -20 degree C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the prot
Intended Use Research Use Only
Alias Symbols BDK, KNG, KNG1
Gene Family ENDOLIG
NCBI Gene Id 3827
Gene Symbol KNG1
Product Format Purified synthetic peptide - lyophilised
Description Similarity: Contains 3 cystatin domains.

Function: (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Additional Information Approx Protein Conc: 5.0 mg/ml
Buffer solution: Acetate salt
Additional Information Label Protein Molar Ratio: Solid phase synthesis
Preservative: None present
Peptide Sequence KRPPGFSPFR
Protein Accession # NP_000884.1
Protein Name Kininogen-1
Reconstitution and Storage Reconstitution: Reconstitute with 1.0ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Aviva Systems Biology recommend that the vial is gently mixed after reconstitution.
Swissprot Id P01042
Datasheets/Manuals Printable datasheet for GWB-18A216
Notice This exact product is now provided by Aviva Systems Biology.
Please visit OPSA10471 to review further and for ordering information.
Description of Target SYNTHETIC HUMAN KALLIDIN II
Species Reactivity Human
Predicted Homology Based on Immunogen Sequence Human
Application ELISA
 

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