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HSV-2 gD Protein (GWB-26532A)

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Additional Information

Name HSV-2 gD Protein (GWB-26532A)
Related Product Names Herpes Simplex Virus-2 gD Recombinant; N/A US6HSV-2 gDGD
Description of Target Entry of HSV into the host cell involves interactions of several viral glycoproteins with cell surface receptors. The virus particle is covered by an envelope which, when bound to specific receptors on the cell surface, will fuse with the cell membrane and create an opening, or pore, through which the virus enters the host cell. The sequential stages of HSV entry are analagous to those of other viruses. At first, complementary receptors on the virus and cell surface bring the two membranes into proximity. In an intermediate state, the two membranes begin to merge, forming a hemifusion state. Finally, a stable entry pore is formed through which the viral envelope contents are introduced to the host cell. The E.Coli derived recombinant protein contains the HSV-2 gD immunodominant regions 266-394 amino acids, fused with 26 kDa GST-tag.
Gene Symbol HSV-2 gD
Alias Symbols HSV-2 gD, Herpes Simplex Virus-2 gD Recombinant
Swissprot ID P03172
Tag GST tag (26 kDa)
Product Format Liquid 25mM Tris (pH 7.2), 1mM EDTA and 50% glycerol
Molecular Weight 40 kDa
Purification Purified by proprietary chromatographic techniques
Specificity Immunoreactive with sera of HSV-infected individuals.
Concentration 1 mg/ml
Purity HSV-2 gD protein is >95% pure as determined by 10% PAGE (coomassie staining)
Source E.coli
Reconstitution and Storage HSV-2 gD, although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze/thaw cycles.
Datasheets/Manuals Printable datasheet for GWB-26532A
Intended Use Research Use Only