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1x96 well plate
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Amyloid precursor protein(APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid(Abeta), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. APP undergoes posttranslational proteolytic processing by alpha-, beta-, and gamma-secretases. Alpha-secretase generates soluble amyloid protein, while beta- and gamma-secretases generate APP components with amyloidogenic features. These 2 processing pathways are mutually exclusive.

Additional Information

Name Human APP ELISA Kit (GWB-KLK5W5)
Related Product Names A4 amyloid protein|A4|A4_HUMAN|AAA|ABETA|ABPP|AD 1|AD1|AICD-50|AICD-57|AICD-59|AID(50)|AID(57)|AID(59)|Alzheimer disease 1|Alzheimer disease amyloid protein|Alzheimer's disease amyloid protein|Amyloid beta (A4) precursor protein|Amyloid beta A4 protein|Am
Short Description Sandwich ELISA kit of Quantitative Detection for Human APP
Immunogen NSO, L18-L688
Sample Type This kit is used for quantitative detection of human APP in cell culture supernates,serum and plasma(heprain, EDTA)
Swissprot ID P05067
Standard Range 312pg/ml-20,000pg/ml. Test has a sensitivity of < 10 pg/ml
Specimen/Volumes Refer to Manual
Concentration Lot Specific
Application ELISA
GI Number 351
Stability Four months at 4C and eight months at -20C.
Reactivity Reactive to Human. There is no detectable cross-reactivity with other relevant proteins.
Kit Size 1x96 well plate
Storage Store at 4C for 6 months, at -20C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Datasheets/Manuals Printable datasheet for GWB-KLK5W5
Intended Use Research Use Only