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1x96 well plate
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BAFF was regularly detected by enzyme-linked immunosorbent assay in brain tissue lysates and in normal spinal fluid, and in astrocytes by double fluorescence microscopy. BAFF was localized in astrocytes close to BAFF-R-expressing immune cells. BAFF receptors were strongly expressed in situ in primary central nervous system(CNS) lymphomas.1 The TNF superfamily member B cell-activating factor(BAFF) plays an important role in humoral immunity and in autoimmune diseases, including RA.Local BAFF gene targeting inhibited proinflammatory cytokine expression, suppressed generation of plasma cells and Th17 cells, and markedly ameliorated joint pathology.2 The B cell activating factor BAFF(BlyS/TALL-1/zTNF4) is a tumor necrosis factor(TNF)-related ligand that promotes B cell survival and binds to three receptors(BCMA, TACI, and the recently described BAFF-R).3 Human BAFF was mapped to chromosome 13q32-34.4 The standard used in this kit is recombinant soluble human BAFF(A134-L295) with the molecular mass of 19.6KDa.

Additional Information

Name Human BAFF ELISA Kit (GWB-ZZD169)
Related Product Names B lymphocyte stimulator| B-cell-activating factor| BAFF| BLyS| CD257| Dendritic cell-derived TNF-like molecule| soluble form| TALL-1| TN13B_HUMAN| TNF- and APOL-related leukocyte expressed ligand 1| TNFSF13B| Tumor necrosis factor ligand superfamily mem
Short Description Sandwich ELISA kit of Quantitative Detection for Human BAFF
Immunogen NSO, A134-L285
Sample Type This kit is used for quantitative detection of human BAFF in cell culture supernates, serum and plasma(heparin, EDTA).
Swissprot ID Q9Y275
Standard Range 62.5pg/ml-4000pg/ml. Test has a sensitivity of < 2 pg/ml
Specimen/Volumes Refer to Manual
Concentration Lot Specific
Application ELISA
GI Number 10673
Stability Two months at 4C and four months at -20C.
Reactivity Reactive to Human. There is no detectable cross-reactivity with other relevant proteins.
Kit Size 1x96 well plate
Storage Store at 4C for 6 months, at -20C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Datasheets/Manuals Printable datasheet for GWB-ZZD169
Intended Use Research Use Only