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In observance of Memorial Day, Genway Biotech office will be closed on Monday, May 28th, 2018

Neurokinin A (4-10)

GWB-114276

06-271-83346

1 mg
$73.60
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Description

Sequence (One Letter Code): DSFVGLM-NH

Sequence: {ASP} {SER} {PHE} {VAL} {GLY} {LEU} {MET}-NH2 C Terminal: NH2

Formula: C34H54N8O10S A structure-activity study of the Neurokinin A (NKA) fragment NKA(4-10) was performed to investigate the importance of amino acid residues for receptor efficacy. potency and affinity at the NK2 receptor in human colon circular muscle. Two series of NKA(4-10) analogues were produced with either L-alanine or the D-enantiomer substituted. Their activities were determined in vitro by means of radioligand binding and isolated smooth muscle pharmacology.

Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

Subcellular Location: Secreted protein.

Similarity: Belongs to the tachykinin family. [1] Wang,Y., Badgery-Parker,T., Lovas,S., Chartrel,N., Vaudry,H., Burcher,E. and Conlon,J.M.
Primary structure and receptor-binding properties of a neurokinin A-related peptide from frog gut
[2] Wang Y., Badgery-Parker T., Lovas S., Chartrel N., Vaudry H., Burcher E., Conlon J.M.
Primary structure and receptor-binding properties of a neurokinin A-related peptide from frog gut.

Additional Information

Name Neurokinin A (4-10)
Related Product Names Neurokinin A (4-10)
NCBI Acc Number P29135
Molecular Weight 1160
Datasheets / Downloads GWB-114276 Datasheet
Swiss Prot Number P29135
Purity > 95%
GI Number 135889
Stability 6-12 months at -20 degree C.
Sequence Length 10
Storage 4 degree C for short term (weeks) and -20 degree C for long term.
Intended Use Research Use Only