PKB (AKT) (460-480) Peptide (GWB-8DA1E0)

GWB-8DA1E0

11-511-248347

0.05 mg
$226.00

Description

Similarity: Contains 1 protein kinase domain.

Buffer: 0.02M Potassium phosphate, 0.15M Sodium Chloride, pH 7.2

Inactivation: Not applicable

Function: General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protein synthesis, partly by playing a role in both insulin-induced phosphorylation of 4E-BP1 and in insulin-induced activation of p70 S6 kinase. Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase.

Additional Information

Name PKB (AKT) (460-480) Peptide (GWB-8DA1E0)
Availability Discontinued
Related Product Names PKB (AKT) (460-480) Peptide; EC 2.7.11.1; RAC-PK-alpha; Protein kinase B; PKB; C-AKT PKB; RACPKB (AKT) (460-480) PeptideAKT1
Swissprot ID P31749
Protein Accession Num NP_001014431.1
NCBI Acc Number NP_001014431.1
Product Format Purified, Liquid
Format Purified, Liquid
Reconstitution and Storage Store at -20C or below prior to opening. Prepare working dilution only prior to immediate use. After opening, aliquot and store at -20C. Avoid multiple freeze/thaw cycles. Expiration date is six months from date of opening product.
Storage Store at -20 C or below prior to opening. Prepare working dilution only prior to immediate use. After opening, aliquot and store at -20 C. Avoid multiple freeze/thaw cycles. Expiration date is six months from date of opening product.
Datasheets/Manuals Printable datasheet for GWB-8DA1E0
Intended Use Research Use Only