Mouse Monoclonal Antiobdy to Glucose-6-phosphate isomerase (GWB-11C388)



0.1 ml


Description: Glucose-6-phosphate isomerase, or phosphoglucose isomerase, also known as GPI. It belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways and it is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in GPI are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Isotype: Mouse IgG1

Clone: 1B7D7

Immunogen: Purified recombinant fragment of human GPI expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Application: Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. 1. Biochem Biophys Res Commun. 2004 Oct 15;323(2):518-22.
2. Biochem Biophys Res Commun. 2006 Oct 20;349(2):838-45.
3. Hum Mutat. 2006 Nov;27(11):1159.
4. Leuk Lymphoma. 2006 Oct;47(10):2234-43.

Additional Information

Name Mouse Monoclonal Antiobdy to Glucose-6-phosphate isomerase (GWB-11C388)
Related Product Names AMF; NLK; PGI; PHI; GNPI; SA-36; GPI Mouse Monoclonal Antiobdy to Glucose-6-phosphate isomerase
Molecular Weight 63kDa
Source Mouse
GI Number 2821
Clonality Monoclonal
Reactivity Human
Storage Store at 4C for long term storage, store at -20C.
Datasheets/Manuals Printable datasheet for GWB-11C388
Intended Use Research Use Only