Anti-IRS1 pS307 Antibody (GWB-5EF9F0)

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100 ug
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Antigen: Human IRS1 pS307

Similarity: Contains 1 PH domain.

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Fraction: Affinity Purified IgG

Function: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).

Additional Information

Name Anti-IRS1 pS307 Antibody (GWB-5EF9F0)
Related Product Names Affinity Purified Anti-Human IRS pS307 (Rabbit); IRS-1 Anti-IRS1 pS307IRS1
Immunogen The immunogen for anti-IRS1 antibody: this affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 298-316 of human IRS1 protein.
Gene Symbol IRS1
Gene Family PLEKH
Gene id 3667
Alias Symbols HIRS 1 antibody, HIRS1 antibody, Insulin Receptor Substrate 1 antibody, IRS 1 antibody
Swissprot ID P35568
Protein Name Insulin receptor substrate 1
Protein Accession Num NP_005535.1
Clone Polyclonal
Host Rabbit
Replacement This antibody may replace item sc-177402 from Santa Cruz Biotechnology.
Homology Human
NCBI Acc Number NP_005535.1
Product Format Liquid (sterile filtered)
Application ELISA, WB, IP
Format Liquid (sterile filtered)
Reconstitution and Storage Store vial at -20 C prior to opening.   This product is stable for several weeks at 4 C as an undiluted liquid.   Dilute only prior to immediate use.   For extended storage aliquot contents and freeze at -20 C or below.   Avoid cycles of freezing and thawing.   Expiration date is one (1) year from date of opening product.
Reactivity Human, Bovine, Mouse, Rat
Application Info ELISA: 1:2,000 - 1:10,000 WB: 1:250 - 1:1,500 IHC: User Optimized
Storage -20C or Colder
Datasheets/Manuals Printable datasheet for GWB-5EF9F0
Species Reactivity Human
Intended Use Research Use Only
Additional Information Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
:: Label: Unconjugated
Preservative: 0.01% (w/v) Sodium Azide
Stabilizer: None