JAK1 (Phospho-Tyr1022) Antibody Blocking Peptide (GWB-A94F30)



0.1 mg
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Function: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

Catalytic Activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Subunit: Interacts with IL31RA, JAKMIP1 and SHB.

Subcellular Location: Intracytoplasmic membrane; Peripheral membrane protein. Note=Wholly intracellular, possibly membrane associated.

Domain: Possesses two phosphotransferase domains. The second one probably contains the catalytic domain (By similarity), while the presence of slight differences suggest a different role for domain 1.

Domain: The FERM domain mediates interaction with JAKMIP1.

Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

Similarity: Contains 1 FERM domain.

Similarity: Contains 1 protein kinase domain.

Similarity: Contains 1 SH2 domain.

Additional Information

Name JAK1 (Phospho-Tyr1022) Antibody Blocking Peptide (GWB-A94F30)
Related Product Names EC; Janus kinase 1; JAK-1 JAK1A; JAK1BJAK1 (Phospho-Tyr1022) Antibody Blocking PeptideJAK1
Swissprot ID P23458
NCBI Acc Number NP_002218.2
Molecular Weight 133277
Datasheets/Manuals Printable datasheet for GWB-A94F30
Intended Use Research Use Only