RXRA Protein (GWB-792913)

GWB-792913

10-663-45692

0
$0.00
Add to Cart

Description

Similarity: Contains 1 nuclear receptor DNA-binding domain.

Function: Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer (By similarity).

Additional Information

Name RXRA Protein (GWB-792913)
Related Product Names Recombinant Human Retinoid X Receptor Alpha; Retinoid X receptor alpha; Nuclear receptor subfamily 2 group B member 1 NR2B1RXR Alpha HumanRXRA
Gene Symbol RXRA
Gene Family NR
Gene id 6256
Alias Symbols Retinoic acid receptor RXR-alpha, Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1, RXRA, NR2B1, FLJ00280, FLJ00318, FLJ16020, FLJ16733, MGC102720, RXR Alpha, RXR-a, RXRA Human, Retinoid X Receptor Alpha Human Recombin
Swissprot ID P19793
Protein Name Retinoic acid receptor RXR-alpha
Description of Target Recombinant Human Retinoid X Receptor Alpha
Protein Accession Num NP_002948.1
Host E. Coli
Peptide Sequence MLGLNGVLKV PAHPSGNMAS FTKHICAICG DRSSGKHYGV YSCEGCKGFF KRTVRKDLTY TCRDNKDCLI DKRQRNRCQY CRYQKCLAMG MKREAVQEER QRGKDRNENE VESTSSANE.
NCBI Acc Number NP_002948.1
Product Format The protein containing 20mM Tris-HCl pH7.5, 0.1M NaCl, 5mM b-Mercaptoethanol. Physical appearance: Sterile filtered colorless solution.
Datasheets / Downloads GWB-792913
Swiss Prot Number P19793
Purity Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Format The protein containing 20mM Tris-HCl pH7.5, 0.1M NaCl, 5mM b-Mercaptoethanol.
Stability Store at 4 C if entire vial will be used within 2-4 weeks. Store, frozen at -20 C for longer periods of time. Avoid multiple freeze-thaw cycles. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Reconstitution and Storage Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Intended Use Research Use Only
:: Product Introduction: The retinoid X receptor (RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors (RAR), thyroid hormone receptors (TR), vitamin D receptors and peroxisome proliferators-activated receptors (PPAR). The RXR family includes three different isoforms; RXR a, b, g. Human RXR a gene is localized on 9q34.9 and encodes two major isoforms (RXR a1, RXR a2). The DNA binding domain of RXR (111-228aa) was purified by using conventional column chromatography techniques.
Product Description: RXRA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 119 amino acids & having a molecular mass of 13.6 kDa.