Mouse Anti Human Tumor Necrosis Factor-alpha Antibody (GWB-782E70)

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GWB-782E70

20-663-46284

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Additional Information

Name Mouse Anti Human Tumor Necrosis Factor-alpha Antibody (GWB-782E70)
Related Product Names TNF a, Tumor Necrosis Factor-alpha, Mouse-Anti, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2 Mouse Anti Human Tumor Necrosis Factor-alphaTNF-a
Description of Target Mouse Anti Human Tumor Necrosis Factor-alpha
Gene Symbol TNF
Gene id 7124
Alias Symbols DIF, TNFA, TNFSF2, TNF-alpha,
Swissprot ID P01375
Protein Name Tumor necrosis factor
Clone NYRhTNFa-E2
Host Mouse
Isotype Mouse IgG1.
Replacement This antibody may replace item sc-101425 from Santa Cruz Biotechnology.
Purity ion exchange.
Application EL, WB, IP, IS
Clonality Monoclonal
Format 1mg/ml in PBS (after reconstitution).
Reconstitution and Storage In lyophilized form, for long periods, store at 4C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20C.
Shipping Conditions: Antibody is shipped lyophilized at ambient temperature.
Reactivity H
Storage In lyophilized form, for long periods, store at 4C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20C.
Datasheets/Manuals Printable datasheet for GWB-782E70
Intended Use Research Use Only
Additional Information Titer: In direct ELISA, using alkaline phosphatase goat anti-mouse Ig (Jackson Laboratories) 1:10,000 dilution will yield 0.7 O.D within 10 minutes.
:: Product Type: Mouse Anti Human Monoclonal.
Reconstitution: Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4C.
:: Product Note: This antibody will bind very well to protein A in a buffer (PBS) containing high salt concentration (3M Nacl).
Immunogen: r.Human TNF-a.
:: Product Introduction: Tumor necrosis factor is a cytokineinvolved in systemic inflammationand is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptoticcell death, cellular proliferation, differentiation, inflammation, tumorigenesisand viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells.Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer.