TNF alpha: Human, Recombinant, E Coli (GWB-6C184F)



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Similarity: Belongs to the tumor necrosis factor family.

Function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.

Additional Information

Name TNF alpha: Human, Recombinant, E Coli (GWB-6C184F)
Availability In Stock
Related Product Names Tumour necrosis factor alpha; TNFA; TNFá; Tumournecrosis factor ligand superfamily 2; TNFSF2; Cachectin;Cachexin; APC1 protein; DIF; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin TNFA; TNFSF2TNF alpha: Human, Recombinant,
Alias Symbols TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2.
Swissprot ID P01375
NCBI Acc Number NP_000585.2
Product Format Liquid
Purity >95% by SDS-PAGE
Application SDS-Page
Format Liquid
Datasheets/Manuals Printable datasheet for GWB-6C184F

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Intended Use Research Use Only
Key Reference Carswell, E et al., (1975) Proc. Natl. Acad. Sci U.S.A. 72 (9): 3666-3670.