Anti- TRADD Antibody (GWB-109CA0)

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GWB-109CA0

18-783-78364

0.1 mg
$573.00

Description

Similarity: Contains 1 death domain. 1. Hsu. H.

Function: Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

Additional Information

Name Anti- TRADD Antibody (GWB-109CA0)
Related Product Names GOAT ANTI HUMAN TRADD (ISOFORM2) TRADDTRADD
Description of Target GOAT ANTI HUMAN TRADD (ISOFORM2)
Immunogen The immunogen for anti-TRADD antibody: peptide sequence C-AAGQNGHEEWVG corresponding to the N-terminus of TRADD (NP_700474).
Gene Symbol TRADD
Gene id 8717
Alias Symbols Hs.89862, MGC11078, TRADD
Swissprot ID Q15628
Protein Name Tumor necrosis factor receptor type 1-associated DEATH domain protein
Protein Accession Num NP_003780.1
Host Goat
Isotype Polyclonal IgG
Homology Human
NCBI Acc Number NP_003780.1
Product Format Purified IgG - liquid
Specificity TRADD
Application ELISA, WB
Clonality Polyclonal
Format Purified
Stability 18 months from date of despatch.
Reconstitution and Storage Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Reactivity Human
Application Info ELISA:    1/128000
Western Blotting:    1 - 3ug/ml
Storage Store at +4 degree C or at -20 degree C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a p
Datasheets/Manuals Printable datasheet for GWB-109CA0
Species Reactivity Human
Intended Use Research Use Only
Key Reference 1. Hsu, H. et al. (1995) The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa-B activation. Cell 81:495-504.
:: Preservative Stabilisers: 0.02% - Sodium Azide
0.5% - Bovine Serum Albumin
Antiserum Preparation: Antisera to human TRADD were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
:: Approx Protein Conc: IgG concentration 0.5 mg/ml
Buffer Solutions: TRIS buffered saline pH7.3