Anti- TRADD Antibody (GWB-109CA0)

GWB-109CA0

18-783-78364

0.1 mg
$573.00

Description

Similarity: Contains 1 death domain. 1. Hsu. H.

Function: Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

Additional Information

Name Anti- TRADD Antibody (GWB-109CA0)
Availability Discontinued
Related Product Names GOAT ANTI HUMAN TRADD (ISOFORM2) TRADDTRADD
Gene Symbol TRADD
Gene id 8717
Alias Symbols Hs.89862, MGC11078, TRADD
Swissprot ID Q15628
Protein Name Tumor necrosis factor receptor type 1-associated DEATH domain protein
Description of Target GOAT ANTI HUMAN TRADD (ISOFORM2)
Protein Accession Num NP_003780.1
Host Goat
Isotype Polyclonal IgG
Immunogen The immunogen for anti-TRADD antibody: peptide sequence C-AAGQNGHEEWVG corresponding to the N-terminus of TRADD (NP_700474).
Homology Human
NCBI Acc Number NP_003780.1
Product Format Purified IgG - liquid
Specificity TRADD
Application ELISA, WB
Clonality Polyclonal
Format Purified
Stability 18 months from date of despatch.
Reconstitution and Storage Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Reactivity Human
Application Info ELISA:    1/128000
Western Blotting:    1 - 3ug/ml
Storage Store at +4 degree C or at -20 degree C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a p
Datasheets/Manuals Printable datasheet for GWB-109CA0
Species Reactivity Human
Intended Use Research Use Only
Key Reference 1. Hsu, H. et al. (1995) The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa-B activation. Cell 81:495-504.
:: Preservative Stabilisers: 0.02% - Sodium Azide
0.5% - Bovine Serum Albumin
Antiserum Preparation: Antisera to human TRADD were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
:: Approx Protein Conc: IgG concentration 0.5 mg/ml
Buffer Solutions: TRIS buffered saline pH7.3