Anti-APC10 Antibody (GWB-189791)

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GWB-189791

18-732-292376

100 ug
$519.00

Description

Similarity: Contains 1 DOC domain.

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

Additional Information

Name Anti-APC10 Antibody (GWB-189791)
Related Product Names Affinity Purified Anti-Human APC10 (Rabbit); APC10; Cyclosome subunit 10 APC10Anti-APC10ANAPC10
Gene Symbol ANAPC10
Gene id 10393
Alias Symbols DOC1, APC10,
Swissprot ID Q9UM13
Protein Name Anaphase-promoting complex subunit 10
Clone Polyclonal
Application Info ELISA: 1:15,000 - 1:80,000 WB: 1:500 - 1:1,500 IP: 1:100 IHC: 1:250 - 1:1,000
Host Rabbit
Immunogen The immunogen for anti-APC10 antibody: this affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the amino terminus of human APC10.
Homology Human
NCBI Acc Number NP_055700.2
Product Format Liquid (sterile filtered)
Application ELISA, WB, IP
Format Liquid (sterile filtered)
Reconstitution and Storage Store vial at -20 C prior to opening.   For extended storage, aliquot contents and freeze at -20 C or below.   Avoid cycles of freezing and thawing.   This product is stable for several weeks at 4 C as an undiluted liquid.   Dilute only prior to immediate use.   Expiration date is one (1) year from date of opening.
Reactivity Human, Bovine, Mouse, Rat
Datasheets/Manuals Printable datasheet for GWB-189791
Storage -20C or Colder
Species Reactivity Human
Lead Time Domestic: within 1-2 weeks delivery | International: 1-2 weeks
Intended Use Research Use Only
Key Reference Grossberger R, et al. (1999) Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex.   J. Biol. Chem. 274:14500-14507. Huang JN, Park I, Ellingson E, Littlepage LE, Pellman D (2001) Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p. J. Cell Biol. 154:85-94. Passmore LA, et al. (2003) Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition. EMBO J. 22:786-796.
Additional Information Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
:: Label: Unconjugated
Preservative: 0.01% (w/v) Sodium Azide
Stabilizer: None