Cdk7 Antibody (GWB-D0D848)

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GWB-D0D848

0.1 mg
$669.00
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Description

Short Description: MOUSE ANTI HUMAN Cdk7

Additional Information

Name Cdk7 Antibody (GWB-D0D848)
Related Product Names MOUSE ANTI HUMAN Cdk7 Cdk7
Gene Symbol CDK7
Gene Family CDK
Gene id 1022
Alias Symbols CAK1, MO15, STK1, CDKN7, p39MO15, CDK7
Swissprot ID P50613
Protein Name Cyclin-dependent kinase 7
Description of Target MOUSE ANTI HUMAN Cdk7
Protein Accession Num NP_001790.1
Clone MO-1
Application Info Western Blotting: 1ug/ml - 10ug/ml
Host Mouse
Immunogen The immunogen for anti-CDK7 antibody: 221 amino acid recombinant fragment of Cdk7 C terminus
Isotype IgG2b
Replacement This antibody may replace item sc-128297 from Santa Cruz Biotechnology.
Homology Human
NCBI Acc Number NP_001790.1
Product Format Purified IgG - liquid
Purification Purified IgG prepared by affinity chromatography on Protein A/G
Specificity Mouse anti Human Cdk7 antibody, clone MO-1 recognizes human Cyclin-dependent kinase 7, also known as 39kDa protein kinase, Cell division protein kinase 7, Serine/threonine-protein kinase 1 and TFIIH basal transcription factor complex kinase subunit. Cdk7 is a 346 amino acid member of the CDC2/CDKX subfamily of serine/threonine family of protein kinases. Cdk7, as part of the CAK complex is involved with the transcription factor TFIIH and is thought to be involved in the control of cell cycle progression, DNA repair and RNA polymerase II (pol II) transcription.
Cdk7 demonstrates ubiquitous muclear expression in normal tissues and is expressed in cancer tissues (Bartkova et al. 1996).
Concentration 1.0mg/ml
Application C, IP, WB
GI Number 4502743
Clonality Monoclonal
Format Solution: Phosphate buffered saline, Stabalizer: 0.08%, Sodium Azide, Form: Purified IgG - liquid
Stability 18 months from date of despatch.
Reconstitution and Storage Store at +4C or at -20C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Reactivity Human
Datasheets/Manuals Printable datasheet for GWB-D0D848
Storage Store at +4C or at -20C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate
Species Reactivity Human
Lead Time Domestic: within 2-3 weeks delivery | International: 2-3 weeks
Intended Use Research Use Only
Key Reference 1. Tassan, J.P. et al. (1994) Cell cycle analysis of the activity, subcellular localization and subunit composition of human CAK (CDK-activating kinase). J. Cell. Biol. 127: 467-478.
Additional Information Histology Positive Control Tissue: HeLa cells fixed with acetone/methanol
:: Preservative Stabilisers: 0.08% - Sodium Azide
:: Approx Protein Conc: IgG concentration 1.0mg/ml
Buffer Solutions: Phosphate buffered saline